Essays about: "Preclinical"
Showing result 1 - 5 of 35 essays containing the word Preclinical.
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1. Representation learning for single cell morphological phenotyping
University essay from Umeå universitet/Institutionen för fysikAbstract : Preclinical research for developing new drugs is a long and expensive procedure. Experiments relying on image acquisition and analysis tend to be low throughput and use reporter systems that may influence the studied cells. READ MORE
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2. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. READ MORE
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3. Evaluation of factors that might affect the grading of heart murmurs in dogs with myxomatous mitral valve disease
University essay from SLU/Dept. of Clinical SciencesAbstract : Myxomatous mitral valve disease (MMVD) is the most common heart disease in dogs. The first sign of MMVD is usually a heart murmur, which most commonly is detected before clinical signs of the disease potentially develop. The preclinical period of MMVD is usually long and can be prolonged with medical treatment. READ MORE
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4. Expanding the application of a novel proteomics tool for drug target and mechanism identification
University essay from Uppsala universitet/Analytisk kemiAbstract : In drug discovery and development, characterization of the drug targets and mechanisms of action is an essential step. ProTargetMiner is a publicly available proteome signature library of anticancer molecules and its automated bioinformatics platform can be used for drug target and mechanism deconvolution. READ MORE
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5. Predictive value of three-dimensional echocardiographic variables on development of myxomatous mitral valve disease in dogs
University essay from SLU/Dept. of Clinical SciencesAbstract : Myxomatous mitral valve disease (MMVD) is the most common acquired cardiovascular disease and the most common cause of congestive heart failure (CHF) in dogs. Cavalier King Charles Spaniels (CKCS) is one of the breeds most commonly affected by MMVD and disease progression has been shown to occur at a younger age among CKCS, when compared to other breeds. READ MORE
