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Showing result 1 - 5 of 32 essays matching the above criteria.
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1. Effects of mixed surfactant system on chemical and physical stability of human growth hormone
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. READ MORE
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2. Accelerating a Molecular Docking Application by Leveraging Modern Heterogeneous Computing Systems
University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)Abstract : In drug development, molecular docking methods aim at characterizing the binding of a drug-like molecule to a protein. In a typical drug development process, a docking task is repeated millions of time, which makes optimization efforts essential. READ MORE
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3. Design, synthesis, and evaluation of 1-phenylethanol and C2 threitol derivatives as non-pyranose galactose-mimicking inhibitors of Galectin-3
University essay from Lunds universitet/Centrum för analys och syntesAbstract : Galectins are cytosolic protein family involved in several biological functions such as cell differentiation, cell migration and apoptosis amongst many others. Their presence is also substantial in diseases including acute inflammation, fibrosis, allergies, and cancer. READ MORE
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4. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. READ MORE
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5. Investigating Minor States of the Oncoprotein N-MYC, with Focus on Proline Cis/Trans Isomerisation using NMR Spectroscopy
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : MYC is a family of three regulator genes that codes for transcription factors. Expression of Myc proteins from MYC genes is found to be deregulated in 70 % of all cancer forms. The three human homologs C-Myc, N-Myc and L-Myc are mainly associated with cancer in the lymphatic system, nerve tissues and lung cancer, respectively. READ MORE