Essays about: "Protein conformation"

Showing result 16 - 20 of 32 essays containing the words Protein conformation.

1. 16. Membrane tension-mediated growth of liposomes : A step closer to synthetic cells

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Sai Sreekar Wunnava Venkata; [2018]
   Keywords : synthetic cells; liposomes; growth; membrane fusion; bottom-up biology; microfluidics;

   Abstract : Living cells are highly complex, making it an extremely challenging task to understand how they function. A possible solution is the bottom-up assembly of non-living components and building up life-like features from scratch, i.e., using synthetic cells as a tool to understand the basic characteristics of life. READ MORE

3. 17. Using Molecular Dynamics and Enhanced Sampling to Predict Binding Poses Beyond The Rigid-Docking Approximation

   University essay from Lunds universitet/Biofysikalisk kemi

   Author : Emil Åberg; [2017]
   Keywords : GAFF; FXR; farnesoid X receptor; MD; computational; enhanced sampling; binding; receptor; ligand; Simulations; Reconnaissance; Metadynamics; Docking; Molecular Dynamics; Protein; AMBER; force fields; structure prediction; crystallography; collective variables; potential; bias potential; biophysical chemistry; biofysikalisk kemi; Chemistry; Technology and Engineering; Biology and Life Sciences;

   Abstract : A computational method is described and tested for prediction of ligand-binding poses between the human farnesoid X receptor and a set of 36 potential agonists, provided by the D3R Grand Challenge 2016. Using tools such as Molecular Docking, Molecular Dynamics, Reconnaissance metadynamics and cluster analysis, the method is an attempt to predict the binding pose without being biased by experimental data. READ MORE

4. 18. Association of genomic breeding values and parental average breeding values with future phenotypic performance in Swedish Red cows

   University essay from SLU/Dept. of Animal Breeding and Genetics

   Author : Christian Bengtsson; [2016]
   Keywords : genomic selection; red dairy cattle; Sweden; genotyping;

   Abstract : The purpose of this study was to compare female genomically enhanced breeding values with parental average breeding values in how well those match the animal’s future phenotypes. At the early years of genomic selection mainly bulls were genotyped, but when the costs decreases, genotyping of heifers becomes more and more interesting. READ MORE

5. 19. Searching for novel protein-protein specificities using a combined approach of sequence co-evolution and local structural equilibration

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Olle Nordesjö; [2016]
   Keywords : Biotechnology; Bioinformatics; Molecular Structure; Protein Conformation; Computing Methodologies; Protein-protein interaction; Binding affinity; Mutation analysis; Amino acid mutation; in-silico binding affinity prediction; Two-component regulatory system; Histidine Kinase; Response Regulator; Prediction; PhoQ; PhoP; Phosphatase;

   Abstract : Greater understanding of how we can use protein simulations and statistical characteristics of biomolecular interfaces as proxies for biological function will make manifest major advances in protein engineering. Here we show how to use calculated change in binding affinity and coevolutionary scores to predict the functional effect of mutations in the interface between a Histidine Kinase and a Response Regulator. READ MORE

6. 20. Protein Microparticles for Printable Bioelectronics

   University essay from Linköpings universitet/Biosensorer och bioelektronik; Linköpings universitet/Tekniska fakulteten

   Author : Hama Nadhom; [2015]
   Keywords : Printed electronic; ink; ink materials; biosensor; protein; immobilization; modification; free enzyme; protein microparticles; enzymatic activity; structural conformation; substrate; Michaelis-Menten kinetic; Km; cross-linking; TMB; stability; pH; temperature; buffer; PBS; solvents; 2-Propanol; Acetonitrile; Ethylene Glycol; incubation; stability; reagent; Glutaraldehyde; CaCO3 template; HRP; BSA-HRP MP; contact area; bioink; leakage diffusion; drop-cast.;

   Abstract : In biosensors, printing involves the transfer of materials, proteins or cells to a substrate. It offers many capabilities thatcan be utilized in many applications, including rapid deposition and patterning of proteins or other biomolecules.However, issues such as stability when using biomaterials are very common. READ MORE