Essays about: "Proximity Extension Assay"

Showing result 1 - 5 of 8 essays containing the words Proximity Extension Assay.

  1. 1. Decoding Hormone Interactions: Investigating Health Status Using Hormone Signatures in Blood

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Stina Brunell; Elis Pettersson Gradin; Victor Englöf; Lovisa Wigertz; Embla Persson; Josephine Maglio; [2023]
    Keywords : PEA; hormone; interaction; blood; protein hormone; proteomic; disease; biomarker;

    Abstract : Hormones are integral molecules in the human body, controlling most body systems and maintaining homeostasis in the body. They function as signal molecules for communication between cells, and are often secreted by one tissue with another as target. READ MORE

  3. 2. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

    University essay from KTH/Proteinvetenskap

    Author : Amelie Carlström; [2023]
    Keywords : PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

    Abstract : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. READ MORE

  4. 3. Profiling the Blood Proteome in Autoimmune Disease Using Proximity Extension Assay

    University essay from KTH/Proteinvetenskap

    Author : Julia Asp; [2023]
    Keywords : Plasma proteomics; proximity extension assay; autoimmune disease; differential expression; machine learning; biomarkers; Plasma proteomik; proximity extension assay; autoimmuna sjukdomar; differentiellt proteinuttryck; maskininlärning; biomarkörer;

    Abstract : Autoimmuna sjukdomar är en samling komplexa, kroniska, inflammatoriska sjukdomstillstånd som kännetecknas av dysreglering av immunsystemet, vilket resulterar i inflammation och skada av vävnader, celler och organ. Dessa sjukdomar har en betydande inverkan på individens livskvalitet och bidrar ofta till ökad dödsrisk där komorbiditeter föreligger. READ MORE

  5. 4. System level analysis of Immune system in children with solid tumors

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Science for Life Laboratory, SciLifeLab

    Author : Nadia Hassan Shamas; [2022]
    Keywords : Immune system in Children; Cancer; Medicines;

    Abstract : Over the last few years, significant immune system changes have been observed in tumor patients exposed to different treatments. Moreover, evaluation and prediction of the responses of treatments given to these patients can become a key component. READ MORE

  6. 5. Immunological Cross-Reactivity : Construction of a Workflow That Enables Cross-Reactivity Predictions

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Alexander Blomlöf; Alvin Unge; Petter Byström; Erika Lindberg; Torbjörn Fries; [2022]
    Keywords : Cross- reactivity; Immunology; Epitope; Paratope; Antibody; Prediction; Substitution analysis; Proximity Extension Assay; Bioinformatic tools;

    Abstract : Cross-reactivity occurs when an antibody binds to the epitope of a protein that is not the targeted antigen. This is problematic in the analysis of immunoassay diagnostics. Detecting a protein incorrectly might cause issues such as incorrect mapping of metabolic conditions for research or diagnosis. READ MORE