Essays about: "Pseudogenes"

Found 1 essay containing the word Pseudogenes.

  1. 1. Orphan G-Protein Coupled Receptors : Can we deorphanize the remaining orphans despite all the challenges?

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Micaela Andersson; [2022]
    Keywords : Deorphanization; Heterodimerization; High-throughput screening; Orphan G-protein Coupled receptor; Pseudogenes; Reversed pharmacology;

    Abstract : G-protein coupled receptors (GPCRs) play a key role in a broad range of biological processes by binding to a wide variety of signaling molecules, which have resulted in 34% of all FDA-approved drugs which target GPCRs. The human genome encodes for approximately 800 GPCR members of which about 140 non-olfactory receptors remain orphans with an unknown function and endogenous ligand. READ MORE