Essays about: "Rituximab"

Found 4 essays containing the word Rituximab.

  1. 1. Improving antibody-based immunotherapy protocols in vitro : Study on optimization of antitumor immunity by antibody-dependent phagocytosis with the monoclonal antibody rituximab

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Giovanni Ferro; [2022]
    Keywords : ;

    Abstract : The monoclonal antibody Rituximab (RTX) has been widely and successfully used to treat non-Burkitt B cell lymphoma in human patients. The combination of immunotherapy with low-dose chemotherapy has increased the success of the treatment and translated into increased patients’ survival. READ MORE

  3. 2. Applying Model Selection on Ligand-Target Binding Kinetic Analysis

    University essay from KTH/Proteinvetenskap

    Author : Klara Djurberg; [2021]
    Keywords : LigandTracer; kinetic models; Rituximab; Bayesian inference; Bayesian model selection; LigandTracer; interaktionsmodeller; Rituximab; Bayesiansk inferens; modellval;

    Abstract : The time-course of interaction formation or breaking can be studied using LigandTracer, and the data obtained from an experiment can be analyzed using a model of ligand-target binding kinetics. There are different kinetic models, and the choice of model is currently motivated by knowledge about the interaction, which is problematic when the knowledge about the interaction is unsatisfactory. READ MORE

  4. 3. Characterization of rituximab-induced B cell depletion and infusion reactions in a human blood loop system

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Mikaela Zekarias; [2020]
    Keywords : Rituximab; CDC; ADCC; infusion reactions; blood loop assay; Fc engineering;

    Abstract : Introduction: Rituximab is a monoclonal antibody used to treat hematological malignancies. The antibody depletes CD20+ B cells via cytotoxic immune mechanisms, such as complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC), which is mainly induced by natural killer (NK) cells. READ MORE

  5. 4. Production of 89Zr for labelling of antibodies to be evaluated preclinically with micro-PET for radioimmunodiagnostics of prostate cancer

    University essay from Lunds universitet/Sjukhusfysikerutbildningen

    Author : Christoffer Svensson; [2008]
    Keywords : Nukleärmedicin; Medicine and Health Sciences;

    Abstract : Introduction: Prostate cancer is the most common cancer type among men in Sweden. The malignant growth is normally a slow process and most patients are diagnosed at an age of 70 or more. However, some are subjected to a more aggressive form that requires an early diagnose to enhance the chances to overcome the disease. READ MORE