Essays about: "S2B"

Found 2 essays containing the word S2B.

1. 1. Comparing consensus modules using S2B and MODifieR

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Daniel McCoy; [2019]
   Keywords : S2B; MODifieR; specific betweenness; betweenness centrality; disease module; module inference; asthma; arthritis;

   Abstract : It is currently understood that diseases are typically not caused by rogue errors in genetics but have both molecular and environmental causes from myriad overlapping interactions within an interactome. Genetic errors, such as that seen by a single-nucleotide polymorphism can lead to a dysfunctional cell, which in turn can lead to systemic disruptions that result in disease phenotypes. READ MORE

3. 2. Evaluating the biological relevance of disease consensus modules : An in silico study of IBD pathology using a bioinformatics approach

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Joel Ströbaek; [2019]
   Keywords : Bioinformatics; Disease module; Consensus module; Disease consensus module; Network medicine; Inflammatory bowel disease; Crohn s disease; Ulcerative colitis; S2B; NSC; Tetralith; MODifieR;

   Abstract : Inflammatory bowel disease encompasses a variety of heterogeneous chronic inflammatory diseases that affect the gastrointestinal tract, where Crohn’s disease and ulcerative colitis are the principal examples. The etiology of these, and many other complex human diseases, remain largely unknown and therefore pose relevant targets for novel research strategies. READ MORE