Essays about: "Secretory Proteins"

Showing result 1 - 5 of 10 essays containing the words Secretory Proteins.

  1. 1. Utsöndrade extracellulära vesiklar (EV) från hästens spolmask Parascaris univalens och deras immunmodulerande roll

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Karin Tufvesson; [2022]
    Keywords : Extracellulära vesiklar; Parascaris univalens; hästens spolmask; ST2; DUSP1; PCR;

    Abstract : Under det senaste decenniet har ett nytt forskningsområde vuxit fram som handlar om kartläggning av extracellulära vesiklar (EV) från parasiter samt hur de kan påverka värddjurets immunförsvar. EV är lipidmembranförsedda blåsor innehållande bland annat proteiner och nukleinsyror och som används för cellkommunikation. READ MORE

  3. 2. Characterization of Giardia intestinalis PAMPs and localization of Giardia’s secretome proteins during infection

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Rafael Marques; [2021]
    Keywords : Excretory-secretory products ESP ; Variable surface proteins VSPs ; High cysteine membrane proteins HCMPs ; Tenascins; Pathogen-associated molecular patterns PAMPs ; Host-parasite interactions;

    Abstract : Giardia intestinalis is a unicellular protozoan parasite responsible for 280 million gastrointestinal infections every year. When colonizing its host, Giardia interacts closely with the small intestine epithelium by attaching to enterocytes and releasing multiple proteins to the extracellular environment. READ MORE

  4. 3. Cytokine production in equine peripheral blood mononuclear cells induced by SvSXP, a Strongylus vulgaris excretory/secretory protein

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Cecilia Winkler; [2021]
    Keywords : Strongylus vulgaris; equine; cytokine; cyathostomins; vaccine; SvSXP;

    Abstract : The most pathogenic intestinal parasite in horses is Strongylus vulgaris (large bloodworm). When a horse becomes infected with S. vulgaris, the larva penetrates the intestinal wall and migrates through the horse's blood vessels. The parasite can cause serious injuries that can lead to severe colic and, in the worst case, death. READ MORE

  5. 4. Optimizing signal peptides for expression of recombinant antibodies in HEK293 cells

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Gustav Myhrinder; [2020]
    Keywords : Signal peptide; antibody; mammalian cell; HEK293; secretory pathway;

    Abstract : Monoclonal antibodies are well-established as a therapeutic in the biopharmaceutical market, targeting a variety of diseases and with 79 approved products by the United States Food and Drug Administration in December 2019. Therapeutic monoclonal antibodies are commonly produced as recombinant proteins in mammalian cell lines, due to their capacity of post-translational modifications, most notably glycosylation. READ MORE

  6. 5. Investigation of immunomodulatory properties of anti-secretory factor in experimental brain tumor models

    University essay from Lunds universitet/Läkarutbildningen

    Author : Hanin Fabiana El-Sabee; Amanda Peetre; [2020]
    Keywords : Antisecretory factor; Immunomodulation; Glioblastoma; Medicine and Health Sciences;

    Abstract : Introduction: Glioblastoma is the most aggressive form of primary brain tumor in adults. Current treatment including chemotherapy poses a limitation due to consequences of systemic toxicity. Further studies for alternative, multimodal treatments are necessary. Antisecretory factor is an endogenous protein. READ MORE