Essays about: "Spatial bispecificity"

Found 1 essay containing the words Spatial bispecificity.

  1. 1. Selection and characterization of bispecific ADAPT molecules for enhanced biodistribution in cancer therapy

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Jesper Borin; [2020]
    Keywords : ABD; ADAPT; HER2; CEACAM6; HSA; Phage display; Cancer therapy; Spatial bispecificity; Half-life extension; Biodistribution;

    Abstract : Established biopharmaceuticals such as antibodies and derivatives thereof are relatively large. In cancer therapy, this creates a steep drug concentration gradient within tumors, leaving cells far from blood vessels effectively untreated. READ MORE