Essays about: "Sprague-Dawley"

Showing result 1 - 5 of 6 essays containing the word Sprague-Dawley.

  1. 1. Effects of Different Load Magnitudes on Longitudinal Growth of Immature Bones

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Emma Dahlgren; [2018]
    Keywords : growth plate; immature bone; metatarsal; longitudinal growth; load magnitude;

    Abstract : In vivo studies of mechanical loading on bone have suggested that load magnitude is one of the parameters that play a vital role in bone adaptation. This study examined how longitudinal growth of immature rat metatarsals is affected by different load magnitudes. READ MORE

  3. 2. The Impact of Compressive and Cyclic Loading Frequency on Longitudinal Growth, Given a Constant Amplitude

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Katya Mehyeddine; [2018]
    Keywords : Biotechnology; Biomechanics; Mechanical stress; Frequency; Longitudinal growth;

    Abstract : Mechanical stress exerted on long bones stimulate ossification and it has been shown that the mechanical variable frequency promotes osteogenesis. This ex-vivo study aimed to investigate how compressive and cyclic loading frequency impacts longitudinal growth of long bones. READ MORE

  4. 3. Quantification of lipid accumulation in the diaphragm after mechanical ventilation

    University essay from Institutionen för biologisk grundutbildning

    Author : Johan Petersson; [2013]
    Keywords : lipid accumulation; diaphragm; mechanical ventilation; IMCL; oil red; ICU; intensive care unit; Sprague-Dawley; rat; ATPase staining; confocal microscopy;

    Abstract : During mechanical ventilation the diaphragm experiences an extreme case of muscleunloading. In many cases this results in respiratory muscle dysfunctions making it difficult towean the patient off the ventilator. One component in this dysfunction is the accumulation ofintramyocellular lipids (IMCL) in the diaphragm muscle fibres. READ MORE

  5. 4. Embryonic Gene Alterations in rats Caused by Exposure to Diabetes and/or Obesity

    University essay from Institutionen för vård och natur

    Author : Ehtesham Ehtesham; [2012]
    Keywords : ;

    Abstract : There is ample evidence that both diabetes as well as obesity leads to various metabolic disturbances that leads to oxidative stress. Oxidative stress has been shown  to  be  associated  with  congenital  malformations  of  which  neural  tube defects  and  cardiac  malformations  are  more  common. READ MORE

  6. 5. Long-term depression in the rat hippocampus as a memory model : Interrogating the role of protein synthesis in NMDA- and mGluR-dependent synaptic plasticity

    University essay from Institutionen för vård och natur

    Author : Sameh Mohammad; [2010]
    Keywords : synaptic plasticity; NMDA; mGluR; Long-term depression; LTD; LTP; fEPSP; hippocampus; protein synthesis; cornu ammonis; plasticity related proteins; Sprague-Dawley rats; action potential;

    Abstract : Long-term potentiation (LTP) and depression (LTD) are important forms of activity-dependent synaptic plasticity believed to play a role in memory at the cellular level. It has previously been described that synthesis of new proteins is needed to maintain LTP longer than a few hours. READ MORE