Essays about: "Srinidhi Varadharajan"

Found 1 essay containing the words Srinidhi Varadharajan.

  1. 1. Building predictive unbound brain-to-plasma concentration ratio (Kp,uu,brain) models

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Srinidhi Varadharajan; [2014]
    Keywords : Biology and Life Sciences;

    Abstract : Abstract The blood-brain barrier (BBB) constitutes a dynamic membrane primarily evolved to protect the brain from exposure to harmful xenobiotics. The distribution of synthesized drugs across the blood-brain barrier (BBB) is a vital parameter to consider in drug discovery projects involving a central nervous system (CNS) target, since the molecules should be capable of crossing the major hurdle, BBB. READ MORE