Essays about: "T7 expression system"

Found 1 essay containing the words T7 expression system.

  1. 1. Process development for the production of a therapeutic Affibody® Molecule

    University essay from Institutionen för biologisk grundutbildning

    Author : Belinda Fridman; [2014]
    Keywords : Affibody® Molecule; HER3; EGFR; HER2; cancer therapy; process development; DOE; multivariate data analysis; E. coli; ABD; plasma half-life; thermolysis; fed-batch; gluconoylation; BL21 DE3 ; T7 expression system;

    Abstract : Recently HER3, member of the epidermal growth factor receptor family (EGFR), has been found to play a crucial role in the development of resistance towards inhibitors that are given to patients with HER1- and HER2-driven cancers. As HER3 is up-regulated or over-activated in several types of human cancers, it is of outmost importance that new innovative drugs target its oncologic activity. READ MORE