Essays about: "TCA-cycle"

Showing result 1 - 5 of 6 essays containing the word TCA-cycle.

  1. 1. Measuring bacterial metabolism and antibioticsusceptibility : using silicon nanowire field-effect transistor.

    University essay from Uppsala universitet/Fasta tillståndets elektronik

    Author : George Alhoush; [2024]
    Keywords : Silicon nanowire field effective transistor; SiNWFET; Ion-selective filed effect transistor; ISFET; Antibiotic susceptibility test; AST; Measuring bacterial metabolism using microchip;

    Abstract : Antimicrobial resistance is considered by many prominent researcher and scientist as a profound global health crisis that us humans must face in the next decade. It is threatening the effectiveness of these once-reliable weapons against bacterial infections and leaving us susceptible to pathogenic agents. READ MORE

  3. 2. Impact of PFAS exposure on the fecal metabolome

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Lisa Johansson; [2022]
    Keywords : Gut metabolites; LC-qTOF-MS; PFAS;

    Abstract : The human gut microbiota plays a crucial role in human health and therefore imbalances in gut microbiota functioning can lead to the development of metabolic disorders. Short-chain fatty acids (SCFA), tricarboxylic acid (TCA) cycle metabolites, bile acids (BA) and other metabolites are the essential compounds for the metabolome. READ MORE

  4. 3. Impact of polychlorinated biphenyl- and organochlorine pesticide exposure on faecal metabolome

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Maja Näsman; [2022]
    Keywords : Gut microbiota; polychlorinated biphenyls; organochlorine pesticides; tricarboxylic acid cycle; bile acids; LC-qTOF-MS.;

    Abstract : The gut microbiota plays a major part in maintaining the health of a human host. Countless of crucial functions in the body, including immune responses, cell signaling and energy metabolism to name a few, are conducted by the gut microbiota and its metabolites. READ MORE

  5. 4. Implementation of a straightforward derivatizationmethod for the simultaneous analysis of short chainfatty acids and tricarboxylic acid cycle metabolitesby LC-qToF-MS.

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Renée Levisson; [2021]
    Keywords : Short-chain fatty acids; tricarboxylic acid TCA cycle; chemical derivatization; 3-nitrophenylhydrazine;

    Abstract : Short-chain fatty acids (SCFAs) and the tricarboxylic acid (TCA) cycle metabolites aresmall hydrophilic compounds that play crucial roles in biological species ranging fromenergy metabolism, immune homeostasis to cellular signalling. There is a need for reliableand precise quantification of these metabolites in biological matrices as they can providecrucial information of metabolic status and potentially be used as diagnostic biomarkersfor different pathological and physiological conditions. READ MORE

  6. 5. Metabolic engineering of Escherichia coli for direct production of 4-hydroxybutyrate from glucose

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Sussan Alipour; [2020]
    Keywords : Escherichia coli; 4- hydroxybutyrate; 4-HB dehydrogenase; 2-oxoglutarate decarboxylase; metabolic engineering; TCA cycle; Succinyl semialdehyde;

    Abstract : Growing concerns of the negative effects on the environment and dependency of fossil fuelsare major driving forces for finding novel sustainable production pathways for plastic.Metabolic engineering has emerged as a powerful tool to enable microorganisms to producenon-native metabolites. READ MORE