Essays about: "TNF-alpha"

Found 3 essays containing the word TNF-alpha.

1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Sam Vadi Dris; [2024]
   Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

   Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

3. 2. Development of a reporter gene assay on an automated platform

   University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

   Author : Fanny Redin; [2021]
   Keywords : Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

   Abstract : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. READ MORE

4. 3. Optimization of a pharmacokinetic assay in a bridging assay format using the Gyrolab immunoassay platform

   University essay from Uppsala universitet/Biokemi

   Author : Ebba Spetsare; [2019]
   Keywords : bridging assay; gyros; affinity; humira; tnf-alfa; pharmacokinetic;

   Abstract : Anti-TNF alpha antibodies were among the first approved antibody drugs and now belongs to the best-selling drugs. Today, several companies are developing biosimilars to those drugs which will increase the access of medications and potentially reduce health care costs. READ MORE