Essays about: "Thiopurine S-Methyltransferase"
Found 1 essay containing the words Thiopurine S-Methyltransferase.
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1. In vitro studies of Thiopurine S-Methyltransferase: Ligand binding interactions and development of a new enzymatic activity assay for TPMTwt, TPMT*6 and TPMT*8
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi; Linköpings universitet/Tekniska fakultetenAbstract : Acute lymphoblastic leukemia, one of the most malignant cancer forms in children is commonly treated with the thiopurine 6-mercaptopurine (6-MP) in combination with a high dose of methotrexate (MTX). 6-Mercaptopurine is in the body metabolized by the enzyme thiopurine S-methyltransferase (TPMT). READ MORE
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