Essays about: "Time-kill experiments"

Found 3 essays containing the words Time-kill experiments.

  1. 1. Screening for double carbapenem therapies effective against multidrug resistant Enterobacteriaceae

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Karin Vickberg; [2019]
    Keywords : Combination therapy; Carbapenem resistance; Carbapenemase; Carbapenem-resistant Enterobacteriaceae CRE ; Carbapenemase-producing Enterobacteriaceae; Klebsiella pneumoniae carbapenemase KPC ; New Delhi metallo-b-lactamase NDM ; Oxacillinase OXA ; Ertapenem ETP ; Doripenem DOR ; Meropenem MEM ; Broth microdilution BMD ; Time-lapse microscopy oCelloScope ; Time-kill experiments; Synergy;

    Abstract : Multidrug resistant bacteria account for one of the biggest threats to human health in the future. One treatment option to be evaluated is antibiotic combination therapy. For this purpose, last- line carbapenems have been suggested, even when bacteria are resistant, e.g. READ MORE

  3. 2. Screening for antibiotic combinationsagainst carbapenem-resistant Gram-negative bacteria

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Marcus Hong; [2018]
    Keywords : ;

    Abstract : Carbapenem-resistant Enterobacteriaceae is a growing problem. Not only are they resistant against carbapenems but the genes that encode for carbapenemase production, are often situated amongst other resistance genes making these bacteria resistant to multiple antibiotic classes. READ MORE

  4. 3. PKPD models for colistin and meropenem on a wild-type and a resistant strain of Pseudomonas aeruginosa

    University essay from Institutionen för farmaceutisk biovetenskap

    Author : Jonathan Lyly; [2011]
    Keywords : meropenem; colistin; pseudomonas aeruginosa; models; pharmacometric models; pharmacokinetic models; PKPD;

    Abstract : Resistant bacteria are becoming more and more of a problem but treatment with antibiotics in combination may overcome and prevent resistance development. The combination of meropenem and colistin against Pseudomonas aeruginosa has been proposed as a promising treatment to increase the bactericidal effect and a synergistic effect has been proposed. READ MORE