Essays about: "Tissue factor"

Showing result 1 - 5 of 101 essays containing the words Tissue factor.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    University essay from Uppsala universitet/Analytisk kemi

    Author : Maryam Dost; [2024]
    Keywords : Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Abstract : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. READ MORE

  3. 2. Expression of complement factor C1r and C1s in human gingival fibroblasts

    University essay from Umeå universitet/Institutionen för odontologi

    Author : Hanna From; [2023]
    Keywords : fibroblasts; pEDS; C1r; C1s;

    Abstract : Background: Periodontitis is an inflammatory condition rendering in degradation of tooth supporting tissue. In the inflammatory process cytokines, amongst others TNF-a, IL-1b and IL-6 play an important role in regulating the immune response. READ MORE

  4. 3. The role of WRKY 15 in xylem development and salt response in Arabidopsis thaliana

    University essay from SLU/Dept. Of Plant Biology

    Author : Johanna Karlsson; [2023]
    Keywords : WRKY15; VND; xylem; salinity; water availability;

    Abstract : Xylem is a water-conducting tissue in vascular plants, that absorbs water from the roots and distributes it throughout the compartments, providing the plant with essential water and nutrients for its cellular processes. The xylem, divided into protoxylem and metaxylem, develops differently according to the various abiotic circumstances, in which transcription factors have a crucial role. READ MORE

  5. 4. Using Generative Adversarial Networks for H&E-to-HER2 Stain Translation in Digital Pathology Images

    University essay from Linköpings universitet/Institutionen för medicinsk teknik

    Author : William Tirmén; [2023]
    Keywords : Machine learning; Artificial intelligence; Digital pathology; Image processing; Generative adversarial networks; Image-to-image translation;

    Abstract : In digital pathology, hematoxylin & eosin (H&E) is a routine stain which is performed on most clinical cases and it often provides clinicians with sufficient information for diagnosis. However, when making decisions on how to guide breast cancer treatment, immunohistochemical staining of human epidermal growth factor 2 (HER2 staining) is also needed. READ MORE

  6. 5. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
    Keywords : Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

    Abstract : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. READ MORE