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1. Filtering of Clinical NGS Data to Improve Low Allele Frequency Variant Calling
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Massive parallel sequencing (NGS) is useful in detecting and later classifying somatic driver mutations in cancer tumours. False-positive variants occur in the NGS workflow and they may be mistaken for low frequency somatic cancer mutations in a patient sample. READ MORE
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