Essays about: "Transdifferentiation"

Found 2 essays containing the word Transdifferentiation.

  1. 1. Modelling conversion of adult skin cells to neurons

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Viktor Drugge; [2018]
    Keywords : Human adult fibroblast; Neuron; Neural conversion; Transdifferentiation; Direct reprogramming; Direct lineage conversion; Simulation; Regulatory gene network; Gene network topology; Gene circuit; Gene dynamics; Physics and Astronomy;

    Abstract : Scientists are now able to directly convert one somatic cell type into another using a procedure known as direct lineage reprogramming or transdifferentiation. In this procedure, transcription factors which are important for initiating a rewriting of the gene expressions are introduced in the cell. READ MORE

  3. 2. Exploring the Potential of CRISPRa and CRISPRi to Systematically Dissect Fate Options in Hematopoiesis

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Alexandra Bäckström; [2017]
    Keywords : Applied biochemistry; tillämpad biokemi; Chemistry; Technology and Engineering;

    Abstract : Advances in our understanding of hematopoietic stem cells (HSCs) have enabled the establishment of differentiation pathways throughout the hematopoietic hierarchy. To further explore the molecular cues governing cell fate options, there is a need to manipulate gene function in a controllable manner. READ MORE