Essays about: "Transwell"

Showing result 1 - 5 of 6 essays containing the word Transwell.

1. 1. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Venus Zafranian; [2021]
   Keywords : Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

   Abstract : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. READ MORE

3. 2. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Maral Simonides; [2021]
   Keywords : Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

   Abstract : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. READ MORE

4. 3. In silico and in vitro determination of substrate specificity for Breast Cancer Resistance Protein (BCRP) transporter at the blood-brain barrier

   University essay from Uppsala universitet/Institutionen för farmaci

   Author : Fen Wang; [2021]
   Keywords : BCRP; substrate specificity; BBB; ATP-binding cassette ABC transporter; Drug transport;

   Abstract : Background The Breast Cancer Resistance Protein (BCRP) drug transporter is important for drug disposition and plays a critical role in regulating drug entry into the brain. Its substrate spectrum overlaps with substrates of Multi Drug Resistance Protein 1 (MDR1, P-gp), which influences and complicates the interpretation of data on drug distribution into tissues (e. READ MORE

5. 4. Toxicological screening of imidazolium based ionic liquids

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Joakim Stenström; [2020]
   Keywords : biology; molecular toxicology; ionic liquids; imidazolium based ionic liquids; toxicology; environmental toxicology;

   Abstract : Ionic liquids are salts that are in liquid form at room temperature. These compounds have been suggested to be environmentally friendly and are proposed to be replacements for commercially available solvents used in laboratory operations today. READ MORE

6. 5. Interactions of Streptococcus equi and Mast Cells: In the Search of Virulence Factors

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Christopher von Beek; [2018]
   Keywords : Streptococcus equi; Streptococcus; mast cells; infection; streptolysin; SLS;

   Abstract : Mast cells are key players of the innate immune system due to their location at the interface of host and pathogen encounters, such as on mucosal surfaces or the skin. Secreting a variety of compounds, they communicate with other immune cells in a highly specific manner. READ MORE