Essays about: "TrkB"

Found 4 essays containing the word TrkB.

1. 1. When the brain loses TrkBactivation : The effects of ketamine on BDNF-TrkB neurotransmission in animal models of depression

   University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

   Author : Hanna Sädbom-Williams; [2021]
   Keywords : Ketamine; Depression; BDNF; TrkB; Animal model; Hippocampus; Prefrontal cortex;

   Abstract : Ketamine is a non-competitive N-methyl-D-aspartate (NMDA)-channel blocker that has recently shown promise in the treatment of major depressive disorder, distinguishing itself from classical anti-depressants through its rapid and lasting effects when given at sub-anaesthetic doses. Animal models of depression are commonly used to research individual mechanisms of action and this literature review aimed to investigate how ketamine influences BDNF-TrkB neurotransmission in the hippocampus and prefrontal cortex within animal models of depression. READ MORE

3. 2. Effect of voluntary exercise on BDNF/TrkB gene expression and alcohol intake.

   University essay from Institutionen för fysik, kemi och biologi; Tekniska högskolan

   Author : Josefine Jonsson; [2012]
   Keywords : Alcohol addiction; BDNF; C57BL 6 mice; Forced swim test; Gene expression; Neurotrophins; TrkB; Voluntary wheel exercise;

   Abstract : Voluntary wheel running is rewarding and believed to activate the same brain reward system as in alcohol and drug addiction. Brain-derived neurotrophic factor (BDNF), a well-known growth factor widely expressed in the brain, is modulated by both voluntary exercise and alcohol consumption. READ MORE

4. 3. Administration of morphine and/or cocaine modulates the expression levels of genes related to plasticity mechanisms in rat hippocampus

   University essay from Institutionen för fysik, kemi och biologi

   Author : Therés Larsson; [2008]
   Keywords : ;

   Abstract : Drugs of abuse regulate the expression of several genes involved in receptor regulation and signalling, transcription factors and cytoskeleton proteins. Due to its implication in long-term memory consolidation, rat hippocampus was selected to identify genes that are differently regulated by morphine and/or cocaine administration. READ MORE

5. 4. Administration of morphine and/or cocaine modulates the expression levels of genes related to plasticity mechanisms in rat hippocampus

   University essay from Institutionen för fysik, kemi och biologi

   Author : Therés Larsson; [2008]
   Keywords : ;

   Abstract : Drugs of abuse regulate the expression of several genes involved in receptor regulation and signalling, transcription factors and cytoskeleton proteins. Due to its implication in long-term memory consolidation, rat hippocampus was selected to identify genes that are differently regulated by morphine and/or cocaine administration. READ MORE