Essays about: "UDP Glucuronosyl-transferase 1A1"
Found 1 essay containing the words UDP Glucuronosyl-transferase 1A1.
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1. IRINOTECANTOXICITY RELATED TO GILBERT´S SYNDROME - COMPARISON OF THREE METHODS FOR GENOTYPING OF UGT1A1 (TA)n
University essay from Institutionen för medicinsk biokemi och mikrobiologiAbstract : Gilbert’s syndrome (GS) occurs in approximately 10% of the European population. The most common cause is homozygosity for UGT1A1*28, which is a TA repeat expansion in the promoter of UGT1A1. It is characterised by intermittent hyperbilirubinemia due to reduced hepatic activity of the enzyme UDP-glucuronosyl-transferase 1A1(UGT1A1). READ MORE
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