Essays about: "Vemurafenib"

Found 1 essay containing the word Vemurafenib.

  1. 1. Development of quantitative methods for the determination of vemurafenib and its metabolites in human plasma

    University essay from Linköpings universitet/Kemi; Linköpings universitet/Tekniska högskolan

    Author : Malin Strömqvist; [2014]
    Keywords : BRAFV600E; HPLC; Human Liver Microsomes; LC-MS MS; Melanoma; Metabolites; Vemurafenib;

    Abstract : Vemurafenib is a potent serine/threonine kinase inhibitor and is registered as Zelboraf® for the treatment of metastatic melanomas harboring BRAFV600E mutations. There is a large individual variation in drug response and the side effects observed among patients treated with Zelboraf® has proven to be severe. READ MORE