Essays about: "Vesicles"

Showing result 1 - 5 of 52 essays containing the word Vesicles.

  1. 1. Exploring alternative surfactants to replace PEG within lipid nanoparticles

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

    Author : Elina Edidovica; [2024]
    Keywords : Lipid nanoparticle; polyethelyne glycol PEG ; alpha-tomatine; N-hexadecyl beta d-maltoside HDM ; DOPC; DPPC; cholesterol; film hydration; stability study; DLS; Cryo-TEM; SAXS; pharmaceutical formulation; Chemistry;

    Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE

  3. 2. Radiotherapy treatment strategy for prostate cancer with lymph node involvement

    University essay from Umeå universitet/Institutionen för fysik

    Author : Amanda Östensson; [2023]
    Keywords : Radiotherapy; prostate cancer; lymph node; gold fiducial marker; multiple target;

    Abstract : Radiotherapy is a common and useful method for treating prostate cancer, often using gold fiducial markers in the prostate as guidance. However, when there is a high risk of lymph node involvement, the independent motion of volumes causes complications in patient positioning since there is a choice between position against the gold fiducial markers or the bone anatomy. READ MORE

  4. 3. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Mawj Jasimalsalih; [2023]
    Keywords : Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Abstract : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. READ MORE

  5. 4. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Keywords : Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Abstract : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. READ MORE

  6. 5. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
    Keywords : Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

    Abstract : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. READ MORE