Essays about: "Yousif Ali Rashid Majid"

Found 1 essay containing the words Yousif Ali Rashid Majid.

  1. 1. Fragment-screening by X-ray crystallography of human vaccinia related kinase 1

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Yousif Ali Rashid Majid; [2020]
    Keywords : Fragment based drug discovery; X-ray crystallography; screening; vaccinia related kinase 1; crystal optimization; fragment library design; differential scanning fluorimetry; Sprint Bioscience;

    Abstract : Fragment-screening by X-ray crystallography (XFS) is an expensive and low throughput fragment drug discovery screening method, and it requires a lot of optimization for each protein target. The advantages with this screening method are that it is very sensitive, it directly gives the three-dimensional structure of the protein-fragment complexes, and false positives are rarely obtained. READ MORE