Essays about: "adhesion proteins"

Showing result 1 - 5 of 16 essays containing the words adhesion proteins.

1. 1. Sortase A coupling of the recombinant partial silk proteins 4Rep-Srt and G-/G5-CT to understand the structure of silk fiber

   University essay from KTH/Proteinvetenskap

   Author : Ellen Adlerz; [2023]
   Keywords : 4RepCT; 4Rep-Srt; G- G5-CT; Sortase A coupling; recombinant silk protein; 4RepCT; 4Rep-Srt; G- G5-CT; Sortase A-koppling; rekombinant silkesprotein;

   Abstract : Spindelsilke är ett intressant material på grund av dess biokompatibilitet och därav användning som biomaterial. Det är jämförbart med konstgjorda material när det gäller styrka och elasticitet, och i kombination med biokompatibiliteten, är spindelsilke eftertraktat inom det medicinska området. READ MORE

3. 2. Generation of a new ADAPT library for stability improvement

   University essay from KTH/Proteinvetenskap

   Author : Sumant Yogesh Salphale; [2023]
   Keywords : Phage display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; protein engineering; cancer detection; Fag-display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; proteinteknik; cancerdetektion;

   Abstract : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. READ MORE

4. 3. Analysis of Stiffness Measurement Methods on Extracellular Vesicles

   University essay from KTH/Tillämpad fysik

   Author : Hanna Kylhammar; [2022]
   Keywords : Extracellular Vesicles; AFM; Atomic Force Microscopy; Fluorescent Microscopy; Extracellulära Vesiklar; AFM; Atomkraftsmikroskopi; Fluorescensmikroskopi;

   Abstract : Extracellular vesicles are important players in cell-to-cell communication and have the potential to be used as biomarkers for decease. The mechanical properties of extracellular vesicles is an active field of research, with new methods and models being developed. READ MORE

5. 4. Characterization of novel bispecific ADAPTs selected for cancer-related targets

   University essay from KTH/Proteinvetenskap

   Author : Blenda Hedin; [2021]
   Keywords : cancer therapy; alternative administration routes; ADAPT; ABD; protein technology; albumin; simultaneous bispecificity; CCL7; CEACAM5; VEGF-A;

   Abstract : Cancer is still one of the most common causes of death world-wide and in parallel there is a need to update the repertoire of therapies that withstand resistance of recurrent cancers. Since the introduction of antibody therapies as anti-cancer pharmaceuticals, recognized as immunotherapy in health care, it has been an increasing field in cancer therapy, as a more targeted treatment compared to chemotherapy. READ MORE

6. 5. Investigation of possible improvements of the stability of bispecific ADAPT proteins

   University essay from KTH/Proteinvetenskap

   Author : Ella Eriksson; [2021]
   Keywords : Protein purification; Affinity chromatography; ABD-derived domain; ADAPT protein; simultan binding;

   Abstract : The aim of the project was to identify positions and amino acids that contribute to improved structure and stability of bispecific ADAPT proteins. During the 20 weeks project period, different amino acid substitutions were analysed to evaluate the effect on the three-helical structure and stability of bispecific ADAPTs targeting human serum albumin (HSA) and tumor necrosis factor α (TNFα). READ MORE