Essays about: "affinity group"

Showing result 1 - 5 of 28 essays containing the words affinity group.

  1. 1. Characterization of Mitilysin Pores by Cryo-electron Microscopy

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Vladimir Novakovic; [2023]
    Keywords : Mitilysin; Mly; Structural Biology; Cryo-EM; pore; toxin; pore forming proteins; pore forming toxins; PFP; PFT;

    Abstract : Pore forming toxins (PFTs) are a large group of proteins found mainly in bacteria with some exceptions found in animals. They bind and form pores in their target membranes and form pores, which leads to cell death. Among these are cholesterol-dependent cytolysins (CDC), which require the presence of cholesterol to bind target membranes. READ MORE

  3. 2. A novel approach for functionalising and separating Tröger's Base Analogues

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Emil Jakobsson; [2023]
    Keywords : Tröger s Base; Synthesis; Chromatography; Supramolecular chemistry; Diastereomers; Organic chemistry; Chemistry;

    Abstract : Tröger’s Base (TB) is a bicyclic compound containing a methanodiazocine group between two aromatic rings. The methylene bridge forces the molecule to have a bent formation; thus, the aromatic rings are close to 90 degrees relative to each other, resulting in a rigid concave aromatic cavity. READ MORE

  4. 3. Exploring a unique pocket in Galectin-8N by the synthesis of D-galactoside-based benzimidazole inhibitors

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sid Bartold; [2023]
    Keywords : organic chemistry; synthesis; gal; gal-8; gal-8N; galectin; galectin-8; galectin-8N; inhibitor; drug development; benzimidazole; galactoside; carbohydrate; carbohydrate chemistry; Suzuki-coupling; Chemistry;

    Abstract : Galectins are a family of glycan-binding proteins where galectin-8 is a part of the subgroup known as tandem-repeat type galectins. Galectin-8 is composed of two homologous CRDs, one N- and one C-terminal CRD. As it stands now, galectin-8N has been found to bind to a larger number of glycans than galectin-8C. READ MORE

  5. 4. Effects of soil factors on pioneer bryophyte species composition

    University essay from Lunds universitet/Examensarbeten i biologi

    Author : Dora Mijić; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Bryophytes play a significant role in various ecological processes, including soil succession and colonization after disturbances. Although they are commonly believed to take up nutrients from soil solutions rather than the soil itself, the influence of soil on their growth and distribution is evident from previous studies. READ MORE

  6. 5. Design, synthesis, and evaluation of 1-phenylethanol and C2 threitol derivatives as non-pyranose galactose-mimicking inhibitors of Galectin-3

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Qrystal Cruz Giron; [2023]
    Keywords : Galectin-3; Galectin-3 inhibitor; 1-phenylethanol; C2 threitol derivative; galactose-mimicking inhibitor; organic chemistry; Chemistry;

    Abstract : Galectins are cytosolic protein family involved in several biological functions such as cell differentiation, cell migration and apoptosis amongst many others. Their presence is also substantial in diseases including acute inflammation, fibrosis, allergies, and cancer. READ MORE