Essays about: "amyotrophic lateral sclerosis"

Showing result 1 - 5 of 10 essays containing the words amyotrophic lateral sclerosis.

  1. 1. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Keywords : Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Abstract : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. READ MORE

  3. 2. Exploring IGF interactions in the context of amyotrophic lateral sclerosis

    University essay from KTH/Proteinvetenskap

    Author : Axelina Schmidt; [2023]
    Keywords : cerebrospinal fluid; plasma; insulin-like growth factors IGFs ; amyotrophic lateral sclerosis; affinity proteomics; cerebrospinalvätska; plasma; insulinliknande tillväxtfaktorer IGF ; amyotrofisk lateralskleros; affinitetsproteomik;

    Abstract : Amyotrofisk lateral skleros (ALS) är en progressiv och dödlig neurodegenerativ sjukdom som påverkar motorneuroner i både hjärnan och ryggraden. Dagens ALS forskning har ett fokus på att skapa en bättre förståelse för både sjukdomsmekanism och de metaboliska processer som bidrar till sjukdomen. READ MORE

  4. 3. Text Prediction using Machine Learning

    University essay from Linköpings universitet/Statistik och maskininlärning

    Author : Muhammad Faizan Khalid; [2022]
    Keywords : Language prediction; sentence completion; LSTM; GRU;

    Abstract : Language modeling is a very broad field and has been used for various purposes for a long period of time to make the lives of people easier. Language modeling is also used for text prediction for mobile keyboards to make the user experience smooth. READ MORE

  5. 4. Development of Sandwich Assays for Potential Protein Biomarkers in Neurodegenerative Diseases

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Jamil Yousef; [2020]
    Keywords : Biomarkers; cerebrospinal fluid; neurodegenerative diseases; neuroproteomics; sandwich assay; suspension bead array.; Biomarkörer; ryggmärgsvätska; neurodegenerativa sjukdomar; neuroproteomik; sandwich assay; suspension bead array.;

    Abstract : As the aging population is increasing worldwide, so is the prevalence of neurodegenerativediseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia(FTD) and amyotrophic lateral sclerosis (ALS). Reliable biomarkers able to aid the diagnosis anddifferentiation of these diseases are needed in order to start the right treatment as early as possible. READ MORE

  6. 5. CRISPR/Cas9 gene-editing in an in vitro model of a familial form of ALS

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Fredrik Nilsson; [2018]
    Keywords : ALS; SOD1; Amyotrophic lateral sclerosis; superoxide dismutase; CRISPR Cas9; sgRNA; stem cell; lentivirus; qPCR; FOXG1; nestin; immunocytochemistry; differentiation; forebrain neural progenitor; Applied Biochemistry; Biology and Life Sciences;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by the degeneration and death of both upper and lower motor neurons for which there is no cure currently available. The degeneration of motor neurons leads to the inability to carry out voluntary movement and death usually occurs 3-5 years after disease onset by respiratory failure. READ MORE