Essays about: "antibody validation"

Showing result 1 - 5 of 7 essays containing the words antibody validation.

  1. 1. Single-cell transcriptomic and antibody-based proteomic analysis of Sertoli cell-specific markers in human testis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Katharina Stanzel; [2023]
    Keywords : ;

    Abstract : The testis is a complex organ responsible for sperm production and hormone synthesis. Spermatogenesis, the process of sperm formation, occurs in the seminiferous tubules and involves the coordinated development of germ cells with the support of Sertoli cells. READ MORE

  3. 2. VISUALIZING CATESTATIN AND CHROMOGRANIN A : An Antibody Validation

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Johan William-Olsson; [2022]
    Keywords : Diabetes; immunology; western blot; flow cytometry; immunofluorescence;

    Abstract : Chromogranin A (CgA) and its cleavage product Catestatin (CST) are two very interesting proteins, especially due to their possible involvement in the development of type 1 diabetes. There are currently only a few primary antibodies against CgA and CST, and the ones that do exist are often only recommended for use on one method. READ MORE

  4. 3. Validation of anti-cytokeratin antibodies used in rapid cancer diagnostics by isoelectric focusing and QCM technology

    University essay from Uppsala universitet/Biokemi

    Author : Reneh Kostines; [2021]
    Keywords : IEF; Isoelectric focusing; QCM; Attana; Cytokeratin; Keratin; Attana; Anti-cytokeratin; cancer; UBC; IDL; epithelial carcinomas; Antibody validation; Biosensor; Biosensors;

    Abstract : Antibodies are Y-shaped proteins. In the human body, antibodies areproduced by plasma cells, mainly T and B cells which are included inthe adaptive immune system. The production of antibodies is stimulatedby antigens. The binding between an antigen-specific antibody and itsantigen can be like the interconnect between a lock and a key. READ MORE

  5. 4. Production and validation of anti-HCV antibodies for viral neutralization

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Megan Olga García Mark; [2020]
    Keywords : Cloning; antibody; infection; HCV; IgG production; molecular biology; cell factory; plasmid design; immunology;

    Abstract : Hepatitis-C Virus (HCV) remains the leading cause of liver transplant in the US and the UK, and the World Health Organization (WHO) estimates that 71 million people are infected worldwide. A vaccine would drastically impact the healthcare-associated burdens that HCV causes globally. READ MORE

  6. 5. Development of Sandwich Assays for Potential Protein Biomarkers in Neurodegenerative Diseases

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Jamil Yousef; [2020]
    Keywords : Biomarkers; cerebrospinal fluid; neurodegenerative diseases; neuroproteomics; sandwich assay; suspension bead array.; Biomarkörer; ryggmärgsvätska; neurodegenerativa sjukdomar; neuroproteomik; sandwich assay; suspension bead array.;

    Abstract : As the aging population is increasing worldwide, so is the prevalence of neurodegenerativediseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia(FTD) and amyotrophic lateral sclerosis (ALS). Reliable biomarkers able to aid the diagnosis anddifferentiation of these diseases are needed in order to start the right treatment as early as possible. READ MORE