Essays about: "band-broadening"

Found 2 essays containing the word band-broadening.

1. 1. Detection of inositol phosphates with HPLC-ICP-AES : Method development

   University essay from Analytisk kemi

   Author : Mieke Wintergerst; [2013]
   Keywords : Inositol phosphates; HPLC; ICP - AES;

   Abstract : Inositol phosphates (IPs) represent a major part of the organic phosphorus found in the environment, which makes their identification and quantification very important. The goal of this project was to explore the possibility of quantification of IPs with inductively coupled plasma - atomic emission spectrometry (ICP - AES). READ MORE

3. 2. Evaluation of Rate Constants from Protein-Ligand Interactions with Weak Affinity Chromatography

   University essay from Institutionen för naturvetenskap, NV

   Author : Daniel Jönsson; [2012]
   Keywords : peak profile method; dissociation association rate constants; weak affinity chromatography; band-broadening;

   Abstract : The paradigm of drug discovery have been to find the strongest possible binder to the target by high-throughput screening (HTS) but high affinity interactions are related to low kinetic off rates and thus result in severe side-effects and non-approved drugs. Lead molecules working in a transient manner (KD > µM) will allow for rapid off rates and possibly less side-effects. READ MORE