Essays about: "bcl"

Showing result 1 - 5 of 6 essays containing the word bcl.

  1. 1. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    University essay from Lunds universitet/Institutionen för immunteknologi

    Author : Johan Thorsson; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. READ MORE

  3. 2. Characterization of MITF gene in crayfish and their possible role in innate immunity

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Yaru Wen; [2020]
    Keywords : Microphthalmia-associated transcription factor; basic Helix-Loop-Helix Leucine Zipper; crayfish; Aphanomyces astaci; immunity;

    Abstract : Microphthalmia-associated transcription factor (MITF) is a tissue-specific transcription factor (TF), with a basic helix-loop-helix leucine zipper (bHLH-LZ) domain, which binds to the canonical E-box sequence (5’-CANNTG-3’) in the promoter region of target genes. In this study, the MITF-like protein was identified in the marbled crayfish (Procambarus virginalis). READ MORE

  4. 3. Finding new therapies Against BCL-2 proteins : The reason behind many resistive tumors

    University essay from Umeå universitet/Institutionen för integrativ medicinsk biologi (IMB)

    Author : Tina Hasson; [2020]
    Keywords : ;

    Abstract : .... READ MORE

  5. 4. Assay development for in situ detection of autophagy-related protein-protein interactions for characterization of colorectal cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : M. Karoliina Hirvonen; [2015]
    Keywords : Autophagy; In situ Proximity Ligation Assay; Colorectal cancer;

    Abstract : Every year, more than a million people are diagnosed with colorectal cancer (CRC) that develops in the large intestine. It is one of the most studied cancers in the world but still more knowledge about how this cancer develops and acts is needed in order to use more effective ways to treat CRC. READ MORE

  6. 5. Effects of protein kinase inhibitors on chronic lymphocytic leukemia (CLL) cells

    University essay from Institutionen för klinisk och experimentell medicin; Hälsouniversitetet

    Author : Hasan Imam; [2009]
    Keywords : ;

    Abstract : B cell Chronic lymphocytic leukemia (B-CLL) is a neoplastic disorder characterized by accumulation of B lymphocytes due to uncontrolled growth and resistance to apoptosis. Src family kinases (SFKs) are non receptor tyrosine kinases present in the cytosol, which couple with downstream B cell receptor signaling and thus mediate growth, survival, proliferation and antiapoptosis. READ MORE