Essays about: "beta cell imaging"
Found 4 essays containing the words beta cell imaging.
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1. Relation between retinal morphology, visual pathway integrity and plasmatic amyloid beta 42 peptide in old and young beagles
University essay from SLU/Dept. of Clinical SciencesAbstract : The spontaneously occurring behavioural syndrome referred to as canine cognitive dysfunction (CCD) is considered the canine counterpart of Alzheimer’s disease (AD). Changes in the retina such as nerve fibre layer (NFL) and ganglion cell complex (GCC) thinning have been observed in Alzheimer’s patients. READ MORE
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2. Modeling of beta-cell Metabolic Activity and Islet Function : a Systems Approach to Type II Diabetes
University essay from KTH/Skolan för teknik och hälsa (STH)Abstract : Diabetes has gained growing attendance as one of the key non communicable diseases (NCD) with the World Health Organization identifying it as the focus of the World Health Day 2016. It is reported that more than 420 million people suffer from diabetes, a number predicted to rise in the coming years. READ MORE
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3. A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT
University essay from SLU/Dept. of Clinical SciencesAbstract : Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. READ MORE
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4. Characterization of the pancreatic β-cell auto antigen targeted by the IC2 monoclonal autoantibody
University essay from Molekylär genetikAbstract : IC2, a well known monoclonal autoantibody, derived from newly diabetic BB rat and seems to be an important biomarker for non-invasive functional imaging of beta cells in vivo. It specially and uniquely binds with pancreatic beta cells as confirmed in some previous studies. READ MORE