Essays about: "bilayer model"

Showing result 1 - 5 of 10 essays containing the words bilayer model.

  1. 1. Diffusion and Camera-Noise Modelling for Analysis of Single-Particle Tracking Movies

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Erik Clarkson; [2022]
    Keywords : reaction-diffusion; camera-noise modelling; single-particle tracking; Gillespie simulations; Physics and Astronomy;

    Abstract : Interactions between T-cells and other body cells is an essential part of the immune system. It involves the binding between surface receptors of the two cells. Specifically, T-cell receptors (TCRs) bind onto pMHC (peptide-loaded major histocompatibility complex) molecules on the partnering cell surface. READ MORE

  2. 2. In silico and in vitro determination of substrate specificity for Breast Cancer Resistance Protein (BCRP) transporter at the blood-brain barrier

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Fen Wang; [2021]
    Keywords : BCRP; substrate specificity; BBB; ATP-binding cassette ABC transporter; Drug transport;

    Abstract : Background The Breast Cancer Resistance Protein (BCRP) drug transporter is important for drug disposition and plays a critical role in regulating drug entry into the brain. Its substrate spectrum overlaps with substrates of Multi Drug Resistance Protein 1 (MDR1, P-gp), which influences and complicates the interpretation of data on drug distribution into tissues (e. READ MORE

  3. 3. GIANT UNILAMELLAR VESICLES FOR PEPTIDE-MEMBRANE INTERACTION STUDIES USING FLUORESCENCE MICROSCOPY

    University essay from Linköpings universitet/Biofysik och bioteknik

    Author : Martin Nilsson; [2020]
    Keywords : Giant unilamellar vesicles; Lipid rafts; Fluorescence microscopy; Drug delivery;

    Abstract : Vesicles are a type of biological or biomimetic particle consisting of one or more often spherical bilayers made up of amphipathic molecules, creating a closed system. They can function as an encapsulating device, holding hydrophilic molecules on the inside of the bilayer membrane(s) or hydrophobic molecules in the non-polar interstitial space in the middle of the bilayers. READ MORE

  4. 4. Constructing supported lipid bilayers from native cell membranes

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Tommy Dam; [2018]
    Keywords : T cells; Model membrane systems; Supported lipid bilayers; SLB; biophysical chemistry; biofysikalisk kemi; Chemistry;

    Abstract : The aim of this MSc-project was to investigate whether it is possible to incorporate native cell membrane components from Jurkat T cells into supported lipid bilayers, SLBs, to produce a model membrane system better resembling the native cell membranes in T cells. The procedure of forming native-like SLBs (nSLB) was adapted from an existing protocol and is done through the deposition of hybrid vesicles onto a cleaned glass slide. READ MORE

  5. 5. Finite Element Analysis of PZT-based Air Flow Sensor

    University essay from Mittuniversitetet/Avdelningen för elektronikkonstruktion

    Author : Xie Chuanliang; [2017]
    Keywords : Air Velocity; PZT; FEA; COMSOL Multiphysics; Bilayer Cantilever;

    Abstract : This thesis proposes a novel air flow sensor based on PZT material which is used to measure air velocity in an experimental tunnel or indoor ventilation. The work focuses on designing and verifying the sensor model through finite element analysis (FEA) simulation using COMSOL Multiphysics software. READ MORE