Essays about: "bioinformatik"
Showing result 1 - 5 of 46 essays containing the word bioinformatik.
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1. Prediction of multiple conformational states of membrane proteins
University essay from Linköpings universitet/BioinformatikAbstract : Predicting protein structures has long been an area of active research in the field ofbioinformatics. Great strides have recently been made in this area by googles DeepMindteam. They developed an AI called AlphaFold which is able to make the most accuratepredictions of protein structures as of date. READ MORE
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2. Analyzing the performance of active learning strategies on machine learning problems
University essay from Uppsala universitet/Avdelningen för systemteknikAbstract : Digitalisation within industries is rapidly advancing and data possibilities are growing daily. Machine learning models need a large amount of data that are well-annotated for good performance. To get well-annotated data, an expert is needed, which is expensive, and the annotation itself could be very time-consuming. READ MORE
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3. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design
University essay from Uppsala universitet/Beräkningsbiologi och bioinformatikAbstract : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. READ MORE
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4. SubKluster: Novel method to bin scaffolds from cereal genomes into subgenomes using substring frequency analysis
University essay from Lunds universitet/Examensarbeten i bioinformatikAbstract : The genome of the Belinda variety of the hexaploid oat (Avena sativa) has recently been sequenced and assembled. This project aims to improve the assembly by clustering the thousands of scaffolds into their three ancestral subgenomes using Principle Component Analysis (PCA) of kmer and repeat-element frequencies. READ MORE
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5. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes
University essay from Lunds universitet/Examensarbeten i bioinformatikAbstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE
