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Found 2 essays matching the above criteria.

1. 1. Assessment of new tracers targeting c-Met for therapeutic effects and possible radioimmunotherapy

   University essay from Uppsala universitet/Institutionen för immunologi, genetik och patologi

   Author : Caroline Lillkull; [2018]
   Keywords : ;

   Abstract : c-Met is a receptor tyrosine kinase that is activated by its ligand hepatocyte growth factor (HGF). c-Met is overexpressed or subject to abnormal activation through mutations or disrupted signaling pathways in various cancers, making it an attractive target for drug therapy with additional potential for imaging properties. READ MORE

3. 2. The genetics of glioma : and the use of dogs as model for human glioma

   University essay from SLU/Dept. of Animal Breeding and Genetics

   Author : Vanja Börjesson; [2016]
   Keywords : c-MET; canine; gene therapy; genome wide association studies GWAS ; next generation sequencing NGS ; glioma;

   Abstract : Glioma is the most common type of primary brain tumor in humans, and the second most common in canines. This tumor type originates from glial cells in the brain and is a genetic disorder caused by mutations in genes regulating important cellular functions. The current diagnosis of glioma is based on histopathological evaluations and gradings. READ MORE