Essays about: "cancer cell line"

Showing result 21 - 25 of 59 essays containing the words cancer cell line.

1. 21. Characterization of cellular enzymatic activity through functional single cell analysis using DropMap

   University essay from Lunds universitet/Institutionen för immunteknologi

   Author : Linnea Gidner; [2020]
   Keywords : Single-cell analysis; enzymatic activity; cell heterogeneity; Biology and Life Sciences;

   Abstract : Assuming normal distribution within cell populations has long been status quo in cellular research. With the fast development of techniques, numerous examples of heterogeneites within isogenic cultures have been unveiled, demonstrating the need of single cell analysis. READ MORE

3. 22. Functional characterization of the SLC38 transporters SNAT6, SNAT8 and SNAT10 using CRISPR-Cas9 knockout in vitro

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Alfred Holmberg; [2020]
   Keywords : SNAT6; SNAT8; SNAT10; SLC38; SLC38a6; SLC38a8; SLC38a10; CRISPR-Cas9; crispr; glutamate-glutamine cycle; ggc; glutamate; glutamine; gaba; hek293;

   Abstract : There are currently over 430 known SLC transporters, over 30% of which have an unknown function. Compared to other transporter gene families, the SLC genes are relatively understudied with many orphan genes. READ MORE

4. 23. Investigation of drug-induced cell cycle responses in high-risk neuroblastoma

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Maryam Sahi; [2020]
   Keywords : Neuroblastoma; chemotherapy resistance; cell cycle arrest; cisplatin; doxorubicin; ATM; Chk1; Wee1; Neuroblastom; kemoterapiresistans; cellcykelarrest; cisplatin; doxorubicin; ATM; Chk1; Wee1;

   Abstract : The childhood cancer neuroblastoma mostly affects children under the age of 2 and comprises 6% of all childhood cancers. Neuroblastoma has very diverse phenotypes caused by both inter- and intra-tumour heterogeneities. The phenotypes are classified as being either low- or high-risk. READ MORE

5. 24. BABAM1 regulation of NLRP3 inflammasome in THP-1 monocyte-like cell lines

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Musa Marrah; [2020]
   Keywords : ;

   Abstract : The nucleotide-binding oligomerization domain–like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a group of multi-protein complex that mediates immune responses through the production of biologically active IL-1β and IL-18. Dysregulation of NLRP3 inflammasome has been linked to various diseases associated with infection, inflammation, and cancer. READ MORE

6. 25. Mapping re-growth following chemotherapy in high-risk neuroblastoma : The research process in laboratory work

   University essay from KTH/Lärande

   Author : Linnéa Ödborn Jönsson; [2019]
   Keywords : Neuroblastoma; Therapy resistance; Relapse; Open-and closed laboratory work; Neuroblastom; Behandlingsresistans; Återfall; Öppna och slutna laborationer;

   Abstract : The aim of the current study is to study characteristics of high-risk cancer cells within the childhood disease neuroblastoma (NB) by mapping regrowth after treatment with the chemotherapy doxorubicin (doxo). The cell-line SK-N-BE(2)-C (BE(2)-C) was used as a model. Results from a previous study by Hultman et al. READ MORE