Essays about: "cancer cell line"

Showing result 6 - 10 of 59 essays containing the words cancer cell line.

  1. 6. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    University essay from Lunds universitet/Institutionen för immunteknologi

    Author : Johan Thorsson; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. READ MORE

  3. 7. Experimental validation of PLAC8 in small intestinal neuroendocrine tumors

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Martin Nilsson; [2023]
    Keywords : ;

    Abstract : Small intestinal neuroendocrine tumors (SI-NETs) are the most common malignant tumor in the small bowel. It is a small-growing cancer with good overall survival 5 years after diagnosis, but no full cure is available when in the metastatic stage. READ MORE

  4. 8. Development of Microfluidic 3D Cell Culture with a Nanocellulose-Based Scaffold for Spheroid Formation as a Potential Tool for Drug Screening

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Sara Payande; [2022]
    Keywords : 3D cell culture; Scaffold; Microfluidics; Layer-by-Layer; Cellulose Nanofibrils; Spheroids; HepG2; 3D cellodling; Matris; Mikrofluidik; Layer-by-Layer; Cellulosa Nanofibriller; Sfäroider; HepG2;

    Abstract : Abstract  Lack of clinical relevance is assumed to be the main reason behind the high failure rate of medical drugs in the very initial phases of clinical trials. Clinical relevance is difficult to achieve with current tools as they lack the biological and physiological cues found in vivo. READ MORE

  5. 9. Validation of promoter and enhancer interactions of a putative cancer gene in Triple Negative breast cancer lines

    University essay from KTH/Proteinvetenskap

    Author : Keerthi Anand Raghavender Anand; [2022]
    Keywords : Triple Negative Breast Cancer cells; Prenylation; Hi-C; HiCap; enhancer-promoter interactions; Trippelnegativa bröstcancerceller; Prenylering; Hi-C; HiCap; interaktioner med förstärkare-promotor;

    Abstract : Trippelnegativ bröstcancer (TNBC) är den mest maligna formen av bröstcancer utan någon framträdande behandlingsbar biomarkör. Således har den djupa återfallsfrekvensen och bristen på behandlingsalternativ öppnat behovet av att förstå TNBC: s etiopatogenes och molekylära mekanism. READ MORE

  6. 10. Validation of enhancer variants modulating haematological toxicity reactions

    University essay from KTH/Proteinvetenskap

    Author : Zandra Norberg; [2022]
    Keywords : Chemotherapy; haematological toxicity reaction; enhancer variants; CRISPRi; K562; Cytostatika; hematologiska toxicitetsreaktioner; enhancer-varianter; CRISPRi; K562;

    Abstract : Omkring 20 miljoner nya cancerfall inträffar över hela världen varje år, och under 2020 uppskattades det att 10 miljoner dödsfall var förknippade med cancer. En av de vanligaste behandlingarna för cancer är cytostatika (cellgifter) som angriper alla snabbväxande celler. READ MORE