Essays about: "capture assay"

Showing result 1 - 5 of 9 essays containing the words capture assay.

1. 1. Towards time-resolved cryo-EM of SARS-CoV-2 replication-transcription complex and Staphylococcus aureus DNA gyrase

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Anna Králová; [2023]
   Keywords : time-resolved cryo-EM; DNA gyrase; SARS-CoV-2; replication-transcription complex; protein purification;

   Abstract : Time-resolved cryo-EM has already provided ground-breaking discoveries in various fields, including structural biology, biochemistry, and drug development. Compared to traditional structural biology methods where mostly stabilized conformations are reconstructed, the main advantage of time-resolved cryo-EM is its ability to capture dynamic processes in biological samples at near-atomic resolution, which allows for studying biological structures as they change and interact in real-time. READ MORE

3. 2. Optimization of a pharmacokinetic assay in a bridging assay format using the Gyrolab immunoassay platform

   University essay from Uppsala universitet/Biokemi

   Author : Ebba Spetsare; [2019]
   Keywords : bridging assay; gyros; affinity; humira; tnf-alfa; pharmacokinetic;

   Abstract : Anti-TNF alpha antibodies were among the first approved antibody drugs and now belongs to the best-selling drugs. Today, several companies are developing biosimilars to those drugs which will increase the access of medications and potentially reduce health care costs. READ MORE

4. 3. Assessment of changes in algal biomass accrual and leaf decomposition along a gradient of increasing agricultural dis-turbance

   University essay from SLU/Dept. of Aquatic Sciences and Assessment

   Author : Maisam Ali; [2015]
   Keywords : leaf decomposition; algal biomass accrual; stream biodiversity;

   Abstract : 1. Anthropogenic activities may impact stream ecosystems by distorting the energetic linkages between the aquatic and adjacent terrestrial habitats, or by modifying the aquatic environment directly. READ MORE

5. 4. Improving anti-drug antibody assay performance in Gyrolab for therapeutic recombinant antibody Infliximab

   University essay from Linköpings universitet/Institutionen för klinisk och experimentell medicin; Linköpings universitet/Hälsouniversitetet

   Author : Bill Cecilia; [2014]
   Keywords : ;

   Abstract : Monoclonal antibodies can be used as targeting therapies for several diseases. One major concern when using these therapies is anti-drug antibodies which may hamper the drugs efficiency. READ MORE

6. 5. Detection of IGF-1 and phosphorylated site in PDGFr using proximity ligation assay

   University essay from SLU/Dept. of Microbiology

   Author : Raghavendra Magalam ; [2014]
   Keywords : PLA; IGF-1; PDGFβr; IgG; recombinant PDGFr; VEGF; solid phase; solution phase;

   Abstract : Proximity ligation assay (PLA) is a novel affinity based method used to detect proteins, protein-protein interactions and post-translational modifications. The detection of target molecules is achieved with the help of oligonucleotide labeled antibodies. READ MORE