Essays about: "caspase"
Showing result 1 - 5 of 9 essays containing the word caspase.
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1. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. READ MORE
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2. Utilizing cytotoxic lymphocytes for indirect shock-and-kill strategy in HIV-1 treatment
University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiAbstract : Despite the existence of a treatment, there is still not a cure for HIV-1 infection and there arearound 700 000 deaths per year from AIDS-related diseases. A major barrier for a cure is theestablishment of latent reservoirs that are impossible to distinguish from healthy cells and thuscan escape the immune system. READ MORE
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3. Protein-protein interactions with and within the NLRP3 inflammasome : Evidence from STRING and literature studies
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Inflammasomes are multiprotein complexes that play a role in the innate immune system. One inflammasome is the NLRP3 inflammasome, which can be activated and primed by different stimuli that bind to pattern recognition receptors (PRRs). READ MORE
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4. Inflammasome : Investigating the effect of NEK7 in the activation of the NLRP3 Inflammasome
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Inflammation is a biological defence mechanism applied by living organisms against foreign invaders. In the response to DAMPs and PAMPs, organisms use inflammatory multi-protein complexes to fight the attackers. The most studied inflammasome proteins are NLRP3, ASC and Caspase-1. READ MORE
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5. The effects of NOX2 and NOX4 inhibitors on panc-1 cell viability
University essay from Högskolan i Skövde/Institutionen för hälsovetenskaperAbstract : Pancreatic cancer is a leading cause of cancer related deaths worldwide and has a low survival rate 1 year after diagnosis. It is therfore important to identify new biomarkers and treatments to improve disease outcome. This experiment investigated the effects of different NOX2 and NOX4 inhibitors on Panc-1 cell lines. READ MORE