Essays about: "cdk"
Showing result 1 - 5 of 8 essays containing the word cdk.
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1. Comparison of infrastructure as code frameworks from a developer perspective
University essay from Linköpings universitet/Institutionen för datavetenskapAbstract : The cloud has become much more important and relevant to the IT industry in recentyears. Instead of buying and maintaining their own physical servers, companies now often opt for renting servers and services from cloud providers. READ MORE
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2. The Classification of Kinase Inhibitors on Five Channel Cell Painting Data Using Deep Learning
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : Purpose This project aims to explore the classification method of kinase inhibitors with five-channel cell painting image data based on the deep learning model. Methods A ResNet50 transfer learning model was used as the starting point to build the deep neural network (DNN) model, where different DNN parameters were selected to make the deep learning model more suitable for the cell painting data. READ MORE
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3. Training Machine Learning-based QSAR models with Conformal Prediction on Experimental Data from DNA-Encoded Chemical Libraries
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : DNA-encoded chemical libraries (DEL) allows an exhaustive chemical space sampling with a large-scale data consisting of compounds produced through combinatorial synthesis. This novel technology was utilized in the early drug discovery stages for robust hit identification and lead optimization. READ MORE
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4. Risk of neutropenia and healthcare resource utilization in patients with metastatic breast cancer treated with CDK4/6 inhibitors in real-world setting
University essay from Örebro universitet/Institutionen för medicinska vetenskaperAbstract : Introduction: In patients with metastatic estrogen-receptor (ER) positive breast cancer, the current standard of care as first or second line treatment is a combination of endocrine therapy with a CDK 4/6-inhibitor. Neutropenia is a dose-limiting toxicity of CDK 4/6 inhibitors leading to dose adjustment and treatment discontinuation in a considerable number of patients. READ MORE
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5. MED13 regulates substrate utilization and bioenergetics in human skeletal muscle
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : The Mediator Complex has an essential function in regulating the transcription of several genes, working as a scaffold between transcription factors and polymerase II. It is composed of 26 subunits, with the kinase, or CDK subunit, being one of the most important for the mediator complex activation. READ MORE
