Essays about: "cellcykel"

Found 5 essays containing the word cellcykel.

  1. 1. Hypoxia-induced expression of HIF-1a and GPR30, in relation to survival, proliferation and apoptosis in MCF-7 and SkBr3 breast cancer cells.

    University essay from Lunds universitet/Läkarutbildningen

    Author : Hanna Chahin; Dianna Jazera; [2021]
    Keywords : hypoxia; breast cancer; GPR30 estrogen receptor; Medicine and Health Sciences;

    Abstract : Introduction: Hypoxia that accompanies tumor growth induces the expression of hypoxiainducible factor a (HIF-1a), in turn mediating the expression of other genes, including G protein-coupled receptor 30 (GPR30), to promote adaption to the hypoxic microenvironment and enable cell proliferation and survival. Nonetheless, this correlation has not been causally explained. READ MORE

  3. 2. Investigation of drug-induced cell cycle responses in high-risk neuroblastoma

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Maryam Sahi; [2020]
    Keywords : Neuroblastoma; chemotherapy resistance; cell cycle arrest; cisplatin; doxorubicin; ATM; Chk1; Wee1; Neuroblastom; kemoterapiresistans; cellcykelarrest; cisplatin; doxorubicin; ATM; Chk1; Wee1;

    Abstract : The childhood cancer neuroblastoma mostly affects children under the age of 2 and comprises 6% of all childhood cancers. Neuroblastoma has very diverse phenotypes caused by both inter- and intra-tumour heterogeneities. The phenotypes are classified as being either low- or high-risk. READ MORE

  4. 3. Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Ximena López Lorenzo; [2020]
    Keywords : Neuroblastoma; NMYC; p53; cell cycle checkpoint; inhibition; regrowth; p21; p27; SKP2; CHK1 2; Neuroblastoma; NMYC; p53; cellcykel checkpoint; hämning; återväxt; p21; p27; SKP2; CHK1 2;

    Abstract : Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. READ MORE

  5. 4. The effect of differential phosphorylation of YB-1 on apoptosis and cell cycle regulation

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Tove Hultman; [2016]
    Keywords : YB-1; apoptos; fosforylering; cellcykel; apoptosis; phosphorylation; cell cycle;

    Abstract : The purpose of this study was to investigate whether different phosphorylated forms of Y-box binding protein (YB-1) can affect the regulation of the cell cycle and/or apoptosis of cancer cells. Recent studies have suggested a key role for YB-1 in the regulation of cancer. READ MORE

  6. 5. The control of the cell cycle with particular emphasis on the G1/S transition

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Erika Andersson; [2014]
    Keywords : G1 S; cellcykel; restriktionspunkt; tumör; cyklin; cdk; cell cycle; restriction point; checkpoint; tumour; cyclin;

    Abstract : Tumour development occurs to a large extent because of dysregulation of the cell cycle. Of particular importance are defects occurring in the G1 phase. The reason why G1 is critical is because of the influence of several signals (external signals as well as cyclins and cdks) on this stage. The G1 phase can be divided into two parts, G1pm and G1ps. READ MORE