Essays about: "chaperone"

Showing result 1 - 5 of 13 essays containing the word chaperone.

  1. 1. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Mawj Jasimalsalih; [2023]
    Keywords : Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Abstract : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. READ MORE

  3. 2. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Josef Getachew; [2023]
    Keywords : α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Abstract : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. READ MORE

  4. 3. Computational Pipeline for Analyses of Genome-Wide Nascent Transcription from PRO-seq Data

    University essay from KTH/Genteknologi

    Author : Serhat Aktay; [2023]
    Keywords : Transcription; functional genomic regions; heat shock response; computational pipeline development; automation.; Genavläsning; genomets funktionella regioner; värmechockrespons; dataanalysutveckling; automatisering;

    Abstract : Celler har en rad olika sätt att försvara sig mot stress för att överleva, främst genom att reglera transkriptionen av gener. En metod för att undersöka hur cellens transkription förändras vid cellulär stress är precision run-on sequencing (PRO-seq). READ MORE

  5. 4. The influence of differentially expressed Nicotina tabacum Rubisco small subunit on holoenzyme structure

    University essay from Uppsala universitet/Strukturbiologi

    Author : Frida Boström; [2022]
    Keywords : Strukturbiologi; Rubisco; Cryo-EM;

    Abstract : Characterization of Rubisco plays a crucial role when it comes to the development and understanding of carbon sequestration in plants. This project took place at BMC in Uppsala, in the Gunn lab, and aimed to structure three Rubisco structures and analyze these with regard to the assembly pathway of the biogenesis of Rubisco but also how fast the reaction of binding of atmospheric carbon dioxide takes place with regard to different isoforms of the small subunit. READ MORE

  6. 5. Characterization of biological role of FKBP51-HSP90 protein-protein interactions in novel knock-in mouse model

    University essay from KTH/Proteinvetenskap

    Author : Shaoxun Xie; [2022]
    Keywords : FK506-binding protein 51kDa; heat shock protein 90kDa; glucocorticoid signaling pathway; dexamethasone; knock-in mouse model; FK506-bindande protein 51kDa; värmechockprotein 90kDa; glucocorticoiders signalvägar; dexamethasone; knock-in musmodell;

    Abstract : Värmechockprotein 90 kDa (HSP90) bildar ett anmärkningsvärt komplicerat nätverk med en mängd olika cochaperones. Komplexet av FK506-bindande protein 51 kDa (FKBP51) och HSP90 förmedlar proteinveckning och funktion, främjar tau aggregation vid Alzheimers sjukdom och påverkar stressrelaterade störningar, fetma, typ två-diabetes, etc. READ MORE