Essays about: "chemoresistance"

Found 4 essays containing the word chemoresistance.

  1. 1. Investigation of Chromatin Organization and mRNA Expression in Drug Treated Human Erythroleukemia Cells

    University essay from KTH/Proteinvetenskap

    Author : Anam Minhas; [2022]
    Keywords : Erythroleukemia cells; mRNA-seq; ATAC-seq; Doxorubicin; Vinblastine; Erytroleukemiceller; mRNA-expression; kromatin; Doxorubicin; Vinblastine;

    Abstract : Syftet med detta projekt var att undersöka hur vanligt använda cancerläkemedel påverkar mRNA-uttryck och kromatinorganisation i humana erytroleukemiceller. Som modell användes K562-celler från en patient i blastocystkris (2), för att utvärdera leukemicellernas svar på cancerläkemedel vinblastin och doxorubicin. READ MORE

  3. 2. The Role of Endoplasmic Reticulum Stress and Hepatic Stellate Cells in Inducing Chemoresistance in Hepatocellular Carcinoma

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Jaafar Khaled; [2021]
    Keywords : Hepatocellular carcinoma; ER-stress; hepatic stellate cells; chemoresistance; doxorubicin; 4μ8C; Hepatocellulärt karcinom; ER-stress; hepatiska stellatceller; kemoresistens; doxorubicin; 4μ8C;

    Abstract : Hepatocellular carcinoma (HCC) is the most common liver malignancy that usually develops in patients suffering from chronic liver diseases. One of the major problems faced in the treatment of HCC is severe chemoresistance. READ MORE

  4. 3. Knockout studies of Panc1 cells

    University essay from KTH/Tillämpad fysik

    Author : Martin Sundin; [2021]
    Keywords : PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. READ MORE

  5. 4. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ojong Tabi Ojong Besong; [2021]
    Keywords : ;

    Abstract : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. READ MORE