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Showing result 1 - 5 of 30 essays matching the above criteria.

  1. 1. Investigation of Adsorption and Retention of Charged Compounds In RPLC

    University essay from Karlstads universitet/Institutionen för ingenjörs- och kemivetenskaper (from 2013)

    Author : Emma Fryxelius; [2022]
    Keywords : adsorption; adsorption isotherm; charged compounds; promethazine hydrochloride; propranolol hydrochloride; mixed-mode; retention; RPLC;

    Abstract : The adsorption isotherm of two weak bases, Promethazine hydrochloride and Propranolol hydrochloride, were determined with isocratic reversed-phase liquid chromatography, with a 60 w% methanol in 20 mM sodium acetate buffer pH 4 as the mobile phase, and calculated by the elution by characteristic points method. The data obtained from the method were then fitted into the Langmuir isotherm and the electrostatically modified Langmuir. READ MORE

  3. 2. Orbit-simulator for downstream processes

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Andreas Malmström; [2022]
    Keywords : Chemical engineering; Process simulation; Downstream processes; Orbit; Preparative chromatography; Python; Lumped Rate Models; Technology and Engineering;

    Abstract : In an ever more digitilized society, the transition is palpable also in the pharmaceutical industry. The control system Orbit was developed at the department of chemical engineering at Lund University, to be able to automate downstream processes based on the ÄKTA-system. READ MORE

  4. 3. A study of the adsorption isotherms of Ion-pair reagents

    University essay from Karlstads universitet

    Author : Mehmet Bilici; [2022]
    Keywords : Tributylamine; adsorption isotherm; liquid-liquid extraction; gas chromatography;

    Abstract : In this project, the optimization of obtaining adsorption isotherms for the ion pair reagent, tributylamine was tested. The goal was to have a better understanding of the chromatographic process when separating biomolecules, such as oligonucleotides. READ MORE

  5. 4. Modeling and simulation of chromatographic separation in Modelon Impact

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Oliver Thelander; [2022]
    Keywords : Chemical engineering; Simulering; Modellering; Kromatografi; Adsorption; Modelica; Modelon Impact; Recirkulation; Simulation; Modeling; Chromatography; Recirculation; Technology and Engineering;

    Abstract : The aim of this master thesis is to implement a previously modeled chromatographic adsorp-tion process from MatLab into the Modelon Impact, a simulation software. Modelon Impact is using Modelica as language syntax that is useful for creating a large system of interconnected models that has the potential to work in different configurations. READ MORE

  6. 5. Double-layer vs single-layer cryogels as a dye affinity chromatography column, comparison study

    University essay from Lunds universitet/Kemiska institutionen

    Author : Thi Hoai Thu Trinh; [2022]
    Keywords : dye-affinity chromatography; single-layer cryogels; double-layer cryogels; protein purification; bovine serum albumin; biochemistry; Chemistry;

    Abstract : Dye affinity chromatography is one of the chromatography techniques which uses dye as a ligand for protein purification. In this study, single-layer poly(acrylamide-allyl glycidyl ether) cryogel was prepared, which contains free epoxy groups at sub-zero temperature. READ MORE