Essays about: "combinatorial chemistry"

Found 5 essays containing the words combinatorial chemistry.

  1. 1. Fragment screening using WAC towards new SMARCA4 inhibitors

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Artur Sahakjan; [2020]
    Keywords : WAC; Fragments; SMARCA4; Library; Fragment Based Drug Discovery FBDD ; Peptide Synthesis; Affinity; Organic chemistry; Organisk kemi; Chemistry;

    Abstract : The drug discovery and development process has changed dramatically during the last decades and the growth of more efficient techniques as high throughput screening combined with combinatorial synthesis using amino acids and carboxylic acids on solid support makes it possible to investigate the affinity of molecules towards a biological target. Fragment based drug discovery (FBDD) has been implemented into different techniques with purpose of discovering new drugs. READ MORE

  2. 2. Implementation of the Todd-Coxeter Algorithm to Finitely Presented Groups

    University essay from Lunds universitet/Matematik (naturvetenskapliga fakulteten)

    Author : Tomas Reed; [2018]
    Keywords : Group Theory; Free Groups; Finitely Presented Groups; Todd-Coxeter Algorithm; Combinatorial Group Theory; Mathematics and Statistics;

    Abstract : This work presents the notion of free groups and the definition of a group using generators and relations. We use the Todd-Coxeter Algorithm in order to solve the coset enumeration problem for the finitely presented groups: $D_4,\, A_4,\, A_5,\, S_3,\, S_4,\, S_5,\, PSL_2(7),\, PSL_2(9)$. READ MORE

  3. 3. Regulating synaptic protein expression by in vivo antibody treatment to reduce epileptogenesis phase in rats

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Vedran Matinjanin; [2017]
    Keywords : Epilepsy epileptogenesis antibody treatment synaptic proteins rat; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Abstract : Epilepsy is a neurological disorder characterized by its debilitating epileptic seizures. There are generalized seizures, which affect the whole brain at once, and focal seizures, which start from one part of the brain. The most common focal epilepsy, is temporal lobe epilepsy representing almost 70% of all focal epilepsies. READ MORE

  4. 4. A Combinatorial Chemistry Approach to the Amorphous Al-In-Zn-O Transparent Oxide Semiconductor System

    University essay from Plasma och beläggningsfysik; Tekniska högskolan

    Author : Pär Arumskog; [2012]
    Keywords : Transparent oxide semiconductors; TOS; amorphous TOS; TAOS; combinatorial chemistry; Al-In-Zn-O; AIZO; a-AIZO; IAZO;

    Abstract : This report describes the successful application of a combinatorial chemistry approach to the evaluation of the amorphous transparent oxide semiconductor Al-In-Zn-O, a-AIZO, for use as channel layers in thin film transistors, TFTs. Many technologies, such as computing and electronic displays, rely on the use of the transistor. READ MORE

  5. 5. Methods for measurement of solubility and dissolution rate of sparingly soluble drugs

    University essay from Lunds universitet/Avdelningen för kemiteknik

    Author : Jesper Larsson; [2009]
    Keywords : Rotating disc; dissolution; pharmacopeial method; intrinsic dissolution; Technology and Engineering;

    Abstract : The drug discovery process has changed dramatically during the last decade. The development of technologies such as combinatorial chemistry has introduced methods to synthesize massive numbers of new diverse compounds. READ MORE