Essays about: "computational pipeline development"
Found 5 essays containing the words computational pipeline development.
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1. Computational Pipeline for Analyses of Genome-Wide Nascent Transcription from PRO-seq Data
University essay from KTH/GenteknologiAbstract : Celler har en rad olika sätt att försvara sig mot stress för att överleva, främst genom att reglera transkriptionen av gener. En metod för att undersöka hur cellens transkription förändras vid cellulär stress är precision run-on sequencing (PRO-seq). READ MORE
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2. Improving Usability of Bioinformatics Software with an Integrated Web Tool System for Cancer Diagnostics
University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)Abstract : Precision cancer medicine is an area of research that involves complex bioinformatics software for the clinical analysis pipelines that sequencing data is passed through. A research team at Karolinska Institutet (KI) is running clinical trials to test new methods of precision cancer medicine and is working on creating a new web application that will be integrated with their two existing applications to aid bioinformaticians in their work of running pipelines and producing clinical reports for the hospitals. READ MORE
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3. Protecting Privacy: Automatic Compression and Encryption of Next-Generation Sequencing Alignment Data
University essay from Uppsala universitet/Experimentell och klinisk onkologiAbstract : As the field of next-generation sequencing (NGS) matures and the technology grows more advanced, it is becoming an increasingly strong tool for solving various biological problems. Harvesting and analysing the full genomic sequence of an individual and comparing it to a reference genome can unravel information about detrimental mutations, in particular ones that give rise to diseases such as cancer. READ MORE
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4. Identification of personalized multi-omic disease modules in asthma
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Asthma is a respiratory syndrome associated with airflow limitation, bronchial hyperresponsiveness and inflammation of the airways in the lungs. Despite the ongoing research efforts, the outstanding heterogeneity displayed by the multiple forms in which this condition presents often hampers the attempts to determine and classify the phenotypic and endotypic biological structures at play, even when considering a limited assembly of asthmatic subjects. READ MORE
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5. Development of a pipeline for patientspecific finite element modelling of the left ventricle of the human heart
University essay from KTH/Numerisk analys, NAAbstract : In order to perform simulations of the human heart using a heart finite element solver developed at the Computational Technology Laboratory at KTH with a data set provided by Philips consisting of surface meshes of a whole heart, the surface mesh has to be converted to a volume mesh. The conversion is manual and time consuming. READ MORE