Essays about: "copy number variations"

Found 5 essays containing the words copy number variations.

1. 1. The relative contribution of CNVs and SNPs to local adaptation in Norway spruce (Picea abies)

   University essay from Uppsala universitet/Växtekologi och evolution; Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Yuxuan Niu; [2022]
   Keywords : CNVs; SNPs; Norway spruce; local adaptation;

   Abstract : In the current environment of severe climate change, studying the adaptability of Norway spruce to the environment, that is, local adaptation is of great significance for helping to protect forest tree species and genetic breeding. As a structural variation, copy number variations (CNVs) have been proved to play an important role in shaping population structure and local adaptation in marine species, going beyond traditional studies focusing only on SNPs. READ MORE

3. 2. Implementing ExomeDepth with a variant filter as a CNV-calling tool for germline clinical diagnostic testing

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Alice Krysén; [2022]
   Keywords : ;

   Abstract : Copy number variations (CNVs) cover approximately 4.9 - 9.5% of the human genome. CNVs are involved in both the development of disease and evolutionary adaptions. READ MORE

4. 3. Antibiotic-Regulated Plasmid Copy Number Variation: A Driver of Antibiotic Resistance?

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Ahmed Eldek; [2019]
   Keywords : antibiotic resistance; plasmid copy number; ddPCR;

   Abstract : Plasmids are small circular DNA molecules within bacterial cells that are separated from the bacterial chromosome and replicate independently. Also, they play a crucial role in the dissemination of antibiotic resistance genes among bacteria through horizontal gene transfer. READ MORE

5. 4. Characterising copy number polymorphisms using next generation sequencing data

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

   Author : Zhiwei Li; [2019]
   Keywords : structural variations; copy number variations; copy number polymorphisms; next generation sequencing; The Northern Sweden Population Health Study; Genome-wide association study;

   Abstract : We developed a pipeline to identify the copy number polymorphisms (CNPs) in the Northern Swedish population using whole genome sequencing (WGS) data. Two different methodologies were applied to discover CNPs in more than 1,000 individuals. READ MORE

6. 5. Copy number variations as potential biomarkers for disease development in Breast Cancer

   University essay from SLU/Dept. of Microbiology

   Author : Reddy Prakash Kancherla; [2011]
   Keywords : Breast cancer; Copy number variation; IFNAR1; VNTR;

   Abstract : Breast cancer is second foremost cause of deaths in women caused by malignant tumor.Comparing genetic profiles of cells surrounding the tumor and blood from same patient may reveal de‐novo somatic aberrations that may predispose normal cells to cancer cells. READ MORE