Essays about: "crystal structure determination"

Showing result 1 - 5 of 6 essays containing the words crystal structure determination.

1. 1. Determination of Proton Beam Waist Positions Using Beam Position Monitors

   University essay from Lunds universitet/Fysiska institutionen; Lunds universitet/European Spallation Source ESS AB; Lunds universitet/Synkrotronljusfysik

   Author : Gustav Gird Fahlström; [2022]
   Keywords : ESS; European Spallation Source; Proton beam; waist; BPM; Method; transverse; beam dynamics; beam physics; Lattice Error; Matrix formalism; Python; trajectory simulation; physics; Physics and Astronomy;

   Abstract : In this work, we examine a novel method for the determination of proton beam waist locations using beam position monitors. Based on the lattice of the final transport line section of the European Spallation Source linac, a simplified version of the beam line composed of quadrupole magnets and correctors is constructed in Python using a matrix formalism. READ MORE

3. 2. Crystallization, optimization, and crystal structure determination of ligands in complex with galectin-8N

   University essay from Lunds universitet/Kemiska institutionen

   Author : George Larsson; [2022]
   Keywords : Biochemistry; Structural Biochemistry; Galectin-8; Protein Crystallization; Chemistry;

   Abstract : This thesis focuses on the protein “galectin-8N” which is a lectin protein that takes part in several physiological functions such as inflammation, autophagy, cell migration, and more. The project has three objectives: to observe and increase the reproducibility of crystallization of two variants (wildtype and mutant) of the human protein galectin-8N and to analyze the binding site when three different novel ligands are each inserted. READ MORE

4. 3. Structure-based design of new antiviral substances against the Venezuelan equine encephalitis virus

   University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

   Author : Elin Öberg; [2022]
   Keywords : x-ray crystallography; protein crystallization; Venezuelan equine encephalitis virus; structure-based drug design; applied biochemistry; Technology and Engineering;

   Abstract : The Venezuelan equine encephalitis virus (VEEV) is a highly infectious alphavirus responsible for severe outbreaks and epidemics in the Americas. The nonstructural protein 2 (nsP2) cysteine protease plays a fundamental role in the VEEV replication process, and is therefore, an attractive drug target for structure-based drug design using x-ray crystallography. READ MORE

5. 4. Characterization, crystallization and two three dimensional structures of the N10- formyltetrahydrofolate synthetase (FTHFS) from the syntrophic acetate oxidizing bacterium Tepidanaerobacter acetatoxydans Re1

   University essay from SLU/Dept. of Molecular Biology (until 131231)

   Author : Roland Bergdahl; [2013]
   Keywords : Biogas; Syntrophic acetate oxidizing bacteria; Tepidanaerobacter acetatoxydans Re1; FTHFS; N10- formyltetrahydrofolate synthetase; Crystallography; Structure determination;

   Abstract : The crystal structure of N10- formyltetrahydrofolate synthetase 1 (FTHFS 1) and N10- formyltetrahydrofolate synthetase 2 (FTHFS 2) from the syntrophic acetate oxidizing bacterium, Tepidanaerobacter acetatoxydans Re1, was solved by x-ray crystallography to a resolution of 2.15 Å, and 2.30 Å resolution, respectively. READ MORE

6. 5. Region-Based Contrast Transfer Function correction for Electron Microscopy Images

   University essay from KTH/Skolan för teknik och hälsa (STH)

   Author : Yohannes Haileyesus Ayele; [2013]
   Keywords : CTF; MelB; TEM; Fourier Transform FT ; Local averaging Lattice filtering ;

   Abstract : Electron crystallography is one of the methods for determining the structure of membrane proteins. However, the resolution that we get from electron crystallography of membrane proteins is limited by crystal disorder and inaccurate determination of contrast transfer function (CTF) parameters. READ MORE