Essays about: "dimerization"

Showing result 1 - 5 of 11 essays containing the word dimerization.

1. 1. Ligand-stimulated cleavage of PDGFR-beta

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Agni Karolina Tsiatsiou; [2023]
   Keywords : ;

   Abstract : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. READ MORE

3. 2. Co-evolutional anaylsis of the Na+,K+-ATPase’s β-subunit dimerization

   University essay from KTH/Tillämpad fysik

   Author : Sebastian Bauer; [2023]
   Keywords : Na ; K -ATPase NKA ; Co-evolution; Dimerization; Direct coupling analysis DCA ; Molecular dynamic MD simulation; Contact filtering; Mapping; Na ; K -ATPas NKA ; Samevolution; Dimerisering; Direkt kopplingsanalys DKA ; Molekylär dynamisk MD simulering; Kontaktfiltrering; Kartläggning;

   Abstract : Does the active membrane transporter, Na+,K+-ATPase dimerize? If it does, whatis the functional benefit? Does it increase or decrease the turnover rate? Theseare still unanswered questions and current research topics. Previous studies havedemonstrated dimerizations in closely related proteins of the P-type ATPase family. READ MORE

4. 3. Expression and purification of pyruvate transporting human mitochondrial pyruvate carrier (MPC) protein complex for structural studies

   University essay from Lunds universitet/Examensarbeten i molekylärbiologi

   Author : Markus Wendler; [2022]
   Keywords : Biology and Life Sciences;

   Abstract : Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. READ MORE

5. 4. Optimization of immunotherapeutic relevant ABD-derived affinity proteins for prolonged serum half-life

   University essay from KTH/Proteinvetenskap

   Author : Ebba Bergström; [2022]
   Keywords : Half-Life extension; Human serum Albumin HSA ; Interleukin 17c IL17c ; ABD-Derived Affinity ProTeins ADAPT ; Protein-based drugs.;

   Abstract : Marknaden för proteinbaserade läkemedel, de så kallade biologiska läkemedlen, är idag en industri som omsätter miljarder. Ett vanligt sätt att utveckla dessa läkemedel på är med hjälp av monoklonala antikroppar då de kan binda till sitt mål med hög specificitet. READ MORE

6. 5. Binuclear zinc transcription factors and the regulation of patulin biosynthesis in the filamentous Ascomycete Penicillium expansum

   University essay from Lunds universitet/Bioteknik (master)

   Author : Robert Hansen Jagrelius; [2021]
   Keywords : secondary fungal metabolism; penicillium expansum; patulin; binuclear zinc transcription factors; dimerization; deepcoil; Biology and Life Sciences;

   Abstract : This thesis investigated the regulation of patulin production in Penicillium expansum in relation to fungal global regulators as well as the cluster-specific binuclear zinc transcription factor (BZTF) patL in silico. It also explored the state of BZTF research in filamentous ascomycetes fungi, and questioned if results in Saccharomyces cerevisiae can be freely translated to other taxonomic groups. READ MORE