Essays about: "dose-response relationship"

Showing result 1 - 5 of 14 essays containing the words dose-response relationship.

  1. 1. Design and analysis of pre-clinical experiments using a method combining multiple comparisons and modeling techniques for dose-response studies

    University essay from Göteborgs universitet/Institutionen för matematiska vetenskaper

    Author : Avijit Singh; [2021-04-20]
    Keywords : pharmacodynamic modeling; dose–response relationship; significance level; multiple comparison procedure; optimal design; MCPMod; dose finding study;

    Abstract : Abstract. Identifying and estimating the dose-response relationship between a compound and a pharmacological endpoint of interest is one of the most important and difficult goals in the preclinical stage of pharmaceutical drug development. READ MORE

  3. 2. Comparison of Multiple Models for Diabetes Using Model Averaging

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Alex Al-Mashat; [2021]
    Keywords : pharmacometrics; population pharmacokinetics; pop-pk; pop-PK diabetes; model averaging; MA; cross-validation; cv; CV; akaike information criterion; Akaike; aic; AIC; MPG; mpg; FPG; fpg; FPI; fpi; HbA1c; hba1c; farmakometri; populationsfarmakokinetik; diabetes; model averaging; MA; cross-validation; cv; CV; akaike; Akaike; aic; AIC; MPG; mpg; FPG; fpg; FPI; fpi; HbA1c; hba1c;

    Abstract : Pharmacometrics is widely used in drug development. Models are developed to describe pharmacological measurements with data gathered from a clinical trial. The information can then be applied to, for instance, safely establish dose-response relationships of a substance. READ MORE

  4. 3. The effect of three days accumulated workload on football players’ perceived fatigue during Pre-Season

    University essay from Gymnastik- och idrottshögskolan, GIH/Institutionen för fysiologi, nutrition och biomekanik

    Author : Pálmar Hreinsson; [2021]
    Keywords : ;

    Abstract : Aim: The aim of the study was to improve the understanding on the relationship between different training- and match load variables and subsequent perceived rating of fatigue. This was done by investigating whether traditionally used workload variables (e.g GPS, HR data) functions as a good indicator of the players' perceived ratings of fatigue. READ MORE

  5. 4. Behavioural effects on Lymnaea stagnalis following sublethal exposure to the antidepressant fluoxetine

    University essay from Lunds universitet/Miljövetenskaplig utbildning

    Author : Jennie Hansson; [2021]
    Keywords : Ecotoxicology; Lymnaea stagnalis; fluoxetine; SSRI; Toxicity; sub-lethal; dose-response relationship; Earth and Environmental Sciences;

    Abstract : The use of selective serotonin reuptake inhibitors (SSRI), a group of antidepressants, increases globally resulting in higher concentrations also in wastewater recipients. These concentrations may cause altered behaviour of aquatic organisms and have effects on whole ecosystem level. READ MORE

  6. 5. Dose-response relationship between dietary protein intake, muscle mass, and strength in elderly European men and women

    University essay from Örebro universitet/Institutionen för hälsovetenskaper

    Author : Oskar Ullberg; [2020]
    Keywords : ;

    Abstract : .... READ MORE